Biomaterial Database

[Characteristics of structure and biological properties of staphylococci isolated from children with HIV-infection]. 2014

Iu V Zakharova

OBJECTIVE Study species composition and factors of pathogenicity of staphylococci isolated from intestine biotope of children with HIV-infection. METHODS 75 strains of staphylococci from HIV-positive and 45 strains from HIV-negatfive children were isolated and identified. Factors of specific adhesion, colonization potential, invasion factors and toxin-formation of staphylococci were studied. RESULTS In HIV-infected children Staphylococcus aureus, Staphylococcus xylosus, Staphylococcus epidermidis dominated. Quantitative level of S. aureus was 1.8 x 10(7) PFU/g. Adhesion, production of hemolysin, DNAse did not differ from the comparison group (p > 0.05). Lipase activity in staphylococci from HIV-infected children was higher than in the control group (p < 0.05). CONCLUSIONS The data obtained reveal some mechanisms of development of endogenous infection in HIV-infected children.

UI	MeSH Term	Description	Entries
D007223	Infant	A child between 1 and 23 months of age.	Infants
D008297	Male		Males
D002675	Child, Preschool	A child between the ages of 2 and 5.	Children, Preschool,Preschool Child,Preschool Children
D005260	Female		Females
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D013203	Staphylococcal Infections	Infections with bacteria of the genus STAPHYLOCOCCUS.	Infections, Staphylococcal,Staphylococcus aureus Infection,Staphylococcal Infection,Staphylococcus aureus Infections
D013211	Staphylococcus aureus	Potentially pathogenic bacteria found in nasal membranes, skin, hair follicles, and perineum of warm-blooded animals. They may cause a wide range of infections and intoxications.
D013212	Staphylococcus epidermidis	A species of STAPHYLOCOCCUS that is a spherical, non-motile, gram-positive, chemoorganotrophic, facultative anaerobe. Mainly found on the skin and mucous membrane of warm-blooded animals, it can be primary pathogen or secondary invader.
D015658	HIV Infections	Includes the spectrum of human immunodeficiency virus infections that range from asymptomatic seropositivity, thru AIDS-related complex (ARC), to acquired immunodeficiency syndrome (AIDS).	HTLV-III Infections,HTLV-III-LAV Infections,T-Lymphotropic Virus Type III Infections, Human,HIV Coinfection,Coinfection, HIV,Coinfections, HIV,HIV Coinfections,HIV Infection,HTLV III Infections,HTLV III LAV Infections,HTLV-III Infection,HTLV-III-LAV Infection,Infection, HIV,Infection, HTLV-III,Infection, HTLV-III-LAV,Infections, HIV,Infections, HTLV-III,Infections, HTLV-III-LAV,T Lymphotropic Virus Type III Infections, Human