-transparent.png){kind=logo}
Restriction fragment length polymorphisms were studied among the Japanese population using 12 polymorphic DNA probes on the q24-q28 region of X chromosome. The frequency distribution for probes p22-33, p482.6a, p43-15, 52A, pPM101, cX33.2 and cpx234, was the same as that for Caucasians, and that for probes 4D-8 and St14-1 (MspI) was slightly different (p less than 0.05). However, it was quite different (p less than 0.01) for probes p114.12, St14-1 (TaqI), 36B-2 and MN12. Probe p114.12 showed no HindIII polymorphism for the Japanese people. On the contrary, probe MN12, which has a low PIC value (0.15) for Caucasians, was found to be useful for Japanese (PIC value = 0.50). These results suggest that 7 DNA probes (p482.6a, p43-15, 52A, St14-1, p114.12 (BclI), 36B-2 and MN12) are useful (PIC greater than 0.42) for linkage analysis of X-linked disease in Japan.
T Taga, and
W Shirahase, and
M Shimada, and
K Kurokawa, and
H Ueyama
September 1988,
Jinrui idengaku zasshi. The Japanese journal of human genetics,
T Taga, and
W Shirahase, and
M Shimada, and
K Kurokawa, and
H Ueyama
January 1984,
Human genetics,
T Taga, and
W Shirahase, and
M Shimada, and
K Kurokawa, and
H Ueyama
January 1986,
Human genetics,
T Taga, and
W Shirahase, and
M Shimada, and
K Kurokawa, and
H Ueyama
June 1993,
The Japanese journal of human genetics,
T Taga, and
W Shirahase, and
M Shimada, and
K Kurokawa, and
H Ueyama
May 1984,
Proceedings of the National Academy of Sciences of the United States of America,
T Taga, and
W Shirahase, and
M Shimada, and
K Kurokawa, and
H Ueyama
January 1989,
Advances in experimental medicine and biology,
T Taga, and
W Shirahase, and
M Shimada, and
K Kurokawa, and
H Ueyama
January 1987,
Methods in enzymology,
T Taga, and
W Shirahase, and
M Shimada, and
K Kurokawa, and
H Ueyama
January 1991,
Parasitology research,
T Taga, and
W Shirahase, and
M Shimada, and
K Kurokawa, and
H Ueyama
January 1990,
Journal of inherited metabolic disease,
T Taga, and
W Shirahase, and
M Shimada, and
K Kurokawa, and
H Ueyama
November 1984,
Somatic cell and molecular genetics,
