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On the basis of 106 patients with malignant atrophic papulosis in the literature, including one case of our own, the clinical, histopathological and nosological features of this disease are reviewed. Histopathologically, the typical papules with central porcelain-white atrophy show broad wedge-shaped necrosis of the connective tissue due to thrombotic occlusions of small vessels in the corium. The disease leads to death in 50% of these cases, mostly due to involvement of the gut and the central nervous system. Malignant atrophic papulosis is the prototype of a disease, in which skin lesions are the primary sign of a systemic disorder demanding the interdisciplinary cooperation of various specialists.
G Burg, and
D Vieluf, and
W Stolz, and
M Landthaler, and
O Braun-Falco
January 2013,
Orphanet journal of rare diseases,
G Burg, and
D Vieluf, and
W Stolz, and
M Landthaler, and
O Braun-Falco
September 1990,
Der Pathologe,
G Burg, and
D Vieluf, and
W Stolz, and
M Landthaler, and
O Braun-Falco
September 2009,
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G Burg, and
D Vieluf, and
W Stolz, and
M Landthaler, and
O Braun-Falco
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G Burg, and
D Vieluf, and
W Stolz, and
M Landthaler, and
O Braun-Falco
March 2005,
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G Burg, and
D Vieluf, and
W Stolz, and
M Landthaler, and
O Braun-Falco
August 2001,
Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete,
G Burg, and
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O Braun-Falco
April 1990,
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G Burg, and
D Vieluf, and
W Stolz, and
M Landthaler, and
O Braun-Falco
September 1968,
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G Burg, and
D Vieluf, and
W Stolz, and
M Landthaler, and
O Braun-Falco
April 2013,
Orphanet journal of rare diseases,
G Burg, and
D Vieluf, and
W Stolz, and
M Landthaler, and
O Braun-Falco
January 2009,
Chirurgia (Bucharest, Romania : 1990),
