Type A aortic dissection with arch entry tear: Surgical experience in 104 patients over a 12-year period. 2016

Wei-Guo Ma, and Wei Zhang, and Long-Fei Wang, and Jun Zheng, and Bulat A Ziganshin, and Paris Charilaou, and Xu-Dong Pan, and Yong-Min Liu, and Jun-Ming Zhu, and Qian Chang, and John A Rizzo, and John A Elefteriades, and Li-Zhong Sun
Department of Cardiovascular Surgery, Beijing Aortic Disease Center, Beijing Anzhen Hospital of Capital Medical University, Beijing Institute of Heart, Lung and Blood Vessel Diseases, and Beijing Engineering Research Center of Vascular Prostheses, Beijing, China; Fu Wai Hospital and Cardiovascular Institute, Chinese Academy of Medical Sciences, Beijing, China; Aortic Institute at Yale-New Haven, Yale University School of Medicine, New Haven, Conn.

OBJECTIVE To evaluate the efficacy of the frozen elephant trunk (FET) and total arch replacement (TAR) technique (FET + TAR) in the management of type A aortic dissection (TAAD) with arch entry tear. METHODS Clinical outcomes were analyzed for 104 TAAD patients with arch entry tear undergoing FET + TAR at 4.7 ± 3.5 days from symptom onset and compared with 728 TAAD patients with entry tears in elsewhere. The mean patient age was 49.3 ± 9.3 years, compared with 45.6 ± 10.8 years in other TAAD patients (P < .001). There were 84 men (80.8%). Hypertension was seen in 84.6% (88/104). RESULTS Operative mortality was 8.6% (9/104). Spinal cord injury occurred in 3 cases (2.9%), stroke in 2 (1.9%), renal failure in 4 (3.8%) and limb ischemia in 2 (1.9%). Follow-up was 100% (95/95) at mean 5.6 ± 2.6 years (range 1.3-11.6). Late death occurred in 2 cases (1.9%). Survival and freedom from late adverse events were 89.2% (95% confidence interval [CI], 81.3%-93.9%) and 85.0% (95% CI, 76.3%-90.8%) at 8 years, respectively. Both the stented and unstented distal aortic segments showed significant trends of false lumen shrinkage and true lumen expansion over time (P < .001). Of the 65 CT scans at mean 4.6 ± 2.9 years postoperatively, the false lumen was completely obliterated in 63. Risk factors for arch entry tear were hypertension (odds ratio [OR], 2.091; 95% CI, 1.186-3.687; P = .011) and age (OR, 1.025; 95% CI, 1.002-1.048; P = .032). CONCLUSIONS TAAD with arch entry tear was treated safely and durably by FET + TAR. Although patients with arch entry tear were somewhat older than other patients, operative mortality was not substantially higher despite their older age and arch location of entry tear. These results argue favorably for the use of the FET + TAR technique in the management of TAAD patients with arch entry tears.

UI MeSH Term Description Entries
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D005260 Female Females
D005500 Follow-Up Studies Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease. Followup Studies,Follow Up Studies,Follow-Up Study,Followup Study,Studies, Follow-Up,Studies, Followup,Study, Follow-Up,Study, Followup
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000293 Adolescent A person 13 to 18 years of age. Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D000368 Aged A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available. Elderly
D000784 Aortic Dissection A tear in the inner layer of the AORTA leading to interstitial HEMORRHAGE, and splitting (dissecting) of the aortic TUNICA MEDIA layer. It typically begins with a tear in the TUNICA INTIMA layer. Aneurysm, Dissecting,Aortic Dissecting Aneurysm,Dissecting Aneurysm,Dissecting Aneurysm Aorta,Aneurysm Aorta, Dissecting,Aneurysm, Aortic Dissecting,Aorta, Dissecting Aneurysm,Aortic Dissecting Aneurysms,Aortic Dissections,Dissecting Aneurysm Aortas,Dissecting Aneurysm, Aortic,Dissecting Aneurysms,Dissection, Aortic
D001013 Aorta, Thoracic The portion of the descending aorta proceeding from the arch of the aorta and extending to the DIAPHRAGM, eventually connecting to the ABDOMINAL AORTA. Aorta, Ascending,Aorta, Descending,Aortic Arch,Aortic Root,Arch of the Aorta,Descending Aorta,Sinotubular Junction,Ascending Aorta,Thoracic Aorta,Aortic Roots,Arch, Aortic,Ascending Aortas,Junction, Sinotubular,Root, Aortic,Sinotubular Junctions

Related Publications

Wei-Guo Ma, and Wei Zhang, and Long-Fei Wang, and Jun Zheng, and Bulat A Ziganshin, and Paris Charilaou, and Xu-Dong Pan, and Yong-Min Liu, and Jun-Ming Zhu, and Qian Chang, and John A Rizzo, and John A Elefteriades, and Li-Zhong Sun
August 1971, Virginia medical monthly,
Wei-Guo Ma, and Wei Zhang, and Long-Fei Wang, and Jun Zheng, and Bulat A Ziganshin, and Paris Charilaou, and Xu-Dong Pan, and Yong-Min Liu, and Jun-Ming Zhu, and Qian Chang, and John A Rizzo, and John A Elefteriades, and Li-Zhong Sun
May 2022, Interactive cardiovascular and thoracic surgery,
Wei-Guo Ma, and Wei Zhang, and Long-Fei Wang, and Jun Zheng, and Bulat A Ziganshin, and Paris Charilaou, and Xu-Dong Pan, and Yong-Min Liu, and Jun-Ming Zhu, and Qian Chang, and John A Rizzo, and John A Elefteriades, and Li-Zhong Sun
January 2021, Interactive cardiovascular and thoracic surgery,
Wei-Guo Ma, and Wei Zhang, and Long-Fei Wang, and Jun Zheng, and Bulat A Ziganshin, and Paris Charilaou, and Xu-Dong Pan, and Yong-Min Liu, and Jun-Ming Zhu, and Qian Chang, and John A Rizzo, and John A Elefteriades, and Li-Zhong Sun
October 2002, Swiss medical weekly,
Wei-Guo Ma, and Wei Zhang, and Long-Fei Wang, and Jun Zheng, and Bulat A Ziganshin, and Paris Charilaou, and Xu-Dong Pan, and Yong-Min Liu, and Jun-Ming Zhu, and Qian Chang, and John A Rizzo, and John A Elefteriades, and Li-Zhong Sun
July 2014, Annals of cardiothoracic surgery,
Wei-Guo Ma, and Wei Zhang, and Long-Fei Wang, and Jun Zheng, and Bulat A Ziganshin, and Paris Charilaou, and Xu-Dong Pan, and Yong-Min Liu, and Jun-Ming Zhu, and Qian Chang, and John A Rizzo, and John A Elefteriades, and Li-Zhong Sun
December 2018, Interactive cardiovascular and thoracic surgery,
Wei-Guo Ma, and Wei Zhang, and Long-Fei Wang, and Jun Zheng, and Bulat A Ziganshin, and Paris Charilaou, and Xu-Dong Pan, and Yong-Min Liu, and Jun-Ming Zhu, and Qian Chang, and John A Rizzo, and John A Elefteriades, and Li-Zhong Sun
July 2009, Korean circulation journal,
Wei-Guo Ma, and Wei Zhang, and Long-Fei Wang, and Jun Zheng, and Bulat A Ziganshin, and Paris Charilaou, and Xu-Dong Pan, and Yong-Min Liu, and Jun-Ming Zhu, and Qian Chang, and John A Rizzo, and John A Elefteriades, and Li-Zhong Sun
August 2025, Vascular specialist international,
Wei-Guo Ma, and Wei Zhang, and Long-Fei Wang, and Jun Zheng, and Bulat A Ziganshin, and Paris Charilaou, and Xu-Dong Pan, and Yong-Min Liu, and Jun-Ming Zhu, and Qian Chang, and John A Rizzo, and John A Elefteriades, and Li-Zhong Sun
August 2011, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery,
Wei-Guo Ma, and Wei Zhang, and Long-Fei Wang, and Jun Zheng, and Bulat A Ziganshin, and Paris Charilaou, and Xu-Dong Pan, and Yong-Min Liu, and Jun-Ming Zhu, and Qian Chang, and John A Rizzo, and John A Elefteriades, and Li-Zhong Sun
April 1990, European heart journal,
Copied contents to your clipboard!