Biomaterial Database

The electrogenic Na/HCO3 cotransporter. 1989

W F Boron, and E L Boulpaep

Department of Cellular and Molecular Physiology, Yale University School of Medicine, New Haven, Connecticut.

UI	MeSH Term	Description	Entries
D007668	Kidney	Body organ that filters blood for the secretion of URINE and that regulates ion concentrations.	Kidneys
D008564	Membrane Potentials	The voltage differences across a membrane. For cellular membranes they are computed by subtracting the voltage measured outside the membrane from the voltage measured inside the membrane. They result from differences of inside versus outside concentration of potassium, sodium, chloride, and other ions across cells' or ORGANELLES membranes. For excitable cells, the resting membrane potentials range between -30 and -100 millivolts. Physical, chemical, or electrical stimuli can make a membrane potential more negative (hyperpolarization), or less negative (depolarization).	Resting Potentials,Transmembrane Potentials,Delta Psi,Resting Membrane Potential,Transmembrane Electrical Potential Difference,Transmembrane Potential Difference,Difference, Transmembrane Potential,Differences, Transmembrane Potential,Membrane Potential,Membrane Potential, Resting,Membrane Potentials, Resting,Potential Difference, Transmembrane,Potential Differences, Transmembrane,Potential, Membrane,Potential, Resting,Potential, Transmembrane,Potentials, Membrane,Potentials, Resting,Potentials, Transmembrane,Resting Membrane Potentials,Resting Potential,Transmembrane Potential,Transmembrane Potential Differences
D008954	Models, Biological	Theoretical representations that simulate the behavior or activity of biological processes or diseases. For disease models in living animals, DISEASE MODELS, ANIMAL is available. Biological models include the use of mathematical equations, computers, and other electronic equipment.	Biological Model,Biological Models,Model, Biological,Models, Biologic,Biologic Model,Biologic Models,Model, Biologic
D002352	Carrier Proteins	Proteins that bind or transport specific substances in the blood, within the cell, or across cell membranes.	Binding Proteins,Carrier Protein,Transport Protein,Transport Proteins,Binding Protein,Protein, Carrier,Proteins, Carrier
D004563	Electrochemistry	The study of chemical changes resulting from electrical action and electrical activity resulting from chemical changes.	Electrochemistries
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D001639	Bicarbonates	Inorganic salts that contain the -HCO3 radical. They are an important factor in determining the pH of the blood and the concentration of bicarbonate ions is regulated by the kidney. Levels in the blood are an index of the alkali reserve or buffering capacity.	Bicarbonate,Bicarbonate Ions,Hydrogen Carbonates,Bicarbonate Ion,Carbonic Acid Ions,Hydrogen Carbonate,Carbonate, Hydrogen,Carbonates, Hydrogen,Ion, Bicarbonate,Ions, Bicarbonate,Ions, Carbonic Acid
D001693	Biological Transport, Active	The movement of materials across cell membranes and epithelial layers against an electrochemical gradient, requiring the expenditure of metabolic energy.	Active Transport,Uphill Transport,Active Biological Transport,Biologic Transport, Active,Transport, Active Biological,Active Biologic Transport,Transport, Active,Transport, Active Biologic,Transport, Uphill
D012964	Sodium	A member of the alkali group of metals. It has the atomic symbol Na, atomic number 11, and atomic weight 23.	Sodium Ion Level,Sodium-23,Ion Level, Sodium,Level, Sodium Ion,Sodium 23
D027982	Sodium-Bicarbonate Symporters	Proteins that cotransport sodium ions and bicarbonate ions across cellular membranes.	SLC4A5 Protein,Electrogenic Sodium Bicarbonate Cotransporter 1,Electrogenic Sodium Bicarbonate Cotransporter 4,Electroneutral Na(+)-Driven Cl-HCO3 Exchanger,Electroneutral Sodium Bicarbonate Exchanger 1,NBC1 Protein,NBC3 Protein,NBC4 Protein,NBCE1 Protein,NBCe2 Protein,NBCn2 Protein,NCBE Protein,Na-HCO3 Symport,SLC4A10 Protein,SLC4A4 Protein,SLC4A7 Protein,SLC4A8 Protein,Sodium Bicarbonate Cotransporter 2,Sodium Bicarbonate Cotransporter 3,Sodium Bicarbonate Symport,Sodium-Bicarbonate Cotransporter,Sodium-Coupled Bicarbonate Transporters,Sodium-driven chloride bicarbonate exchanger,Solute Carrier Family 4 Member 10,Solute Carrier Family 4 Member 4,Solute Carrier Family 4 Member 5,Solute Carrier Family 4 Member 7,Solute Carrier Family 4 Member 8,Solute Carrier Family 4, Sodium Bicarbonate Cotransporter, Member 10,Solute Carrier Family 4, Sodium Bicarbonate Cotransporter, Member 4,Solute Carrier Family 4, Sodium Bicarbonate Cotransporter, Member 5,Solute Carrier Family 4, Sodium Bicarbonate Cotransporter, Member 7,Solute Carrier Family 4, Sodium Bicarbonate Cotransporter, Member 8,k-NBC3 Protein,Bicarbonate Symport, Sodium,Bicarbonate Transporters, Sodium-Coupled,Cotransporter, Sodium-Bicarbonate,Na HCO3 Symport,Protein, NBC1,Protein, NBC3,Protein, NBC4,Protein, NBCE1,Protein, NBCe2,Protein, NBCn2,Protein, SLC4A10,Protein, SLC4A4,Protein, SLC4A5,Protein, SLC4A7,Protein, SLC4A8,Protein, k-NBC3,Sodium Bicarbonate Cotransporter,Sodium Bicarbonate Symporters,Sodium Coupled Bicarbonate Transporters,Sodium driven chloride bicarbonate exchanger,Symport, Na-HCO3,Symport, Sodium Bicarbonate,Symporters, Sodium-Bicarbonate,Transporters, Sodium-Coupled Bicarbonate,k NBC3 Protein