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Deep Brain Stimulation of the Fornix: Engaging Therapeutic Circuits and Networks in Alzheimer Disease. 2016

Nathan C Rowland, and Francesco Sammartino, and Jennifer C Tomaszczyk, and Andres M Lozano
Division of Neurosurgery, University of Toronto, Toronto Western Hospital, Toronto, Ontario, Canada.

UI MeSH Term Description Entries
D008297 Male Males
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000544 Alzheimer Disease A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57) Acute Confusional Senile Dementia,Alzheimer's Diseases,Dementia, Alzheimer Type,Dementia, Senile,Presenile Alzheimer Dementia,Senile Dementia, Alzheimer Type,Alzheimer Dementia,Alzheimer Disease, Early Onset,Alzheimer Disease, Late Onset,Alzheimer Sclerosis,Alzheimer Syndrome,Alzheimer Type Senile Dementia,Alzheimer's Disease,Alzheimer's Disease, Focal Onset,Alzheimer-Type Dementia (ATD),Dementia, Presenile,Dementia, Primary Senile Degenerative,Early Onset Alzheimer Disease,Familial Alzheimer Disease (FAD),Focal Onset Alzheimer's Disease,Late Onset Alzheimer Disease,Primary Senile Degenerative Dementia,Senile Dementia, Acute Confusional,Alzheimer Dementias,Alzheimer Disease, Familial (FAD),Alzheimer Diseases,Alzheimer Type Dementia,Alzheimer Type Dementia (ATD),Alzheimers Diseases,Dementia, Alzheimer,Dementia, Alzheimer-Type (ATD),Familial Alzheimer Diseases (FAD),Presenile Dementia,Sclerosis, Alzheimer,Senile Dementia
D046690 Deep Brain Stimulation Therapy for MOVEMENT DISORDERS, especially PARKINSON DISEASE, that applies electricity via stereotactic implantation of ELECTRODES in specific areas of the BRAIN such as the THALAMUS. The electrodes are attached to a neurostimulator placed subcutaneously. Brain Stimulation, Deep,Electrical Stimulation of the Brain,Brain Stimulations, Deep,Deep Brain Stimulations,Stimulation, Deep Brain,Stimulations, Deep Brain
D020712 Fornix, Brain Heavily myelinated fiber bundle of the TELENCEPHALON projecting from the hippocampal formation to the HYPOTHALAMUS. Some authorities consider the fornix part of the LIMBIC SYSTEM. The fimbria starts as a flattened band of axons arising from the subiculum and HIPPOCAMPUS, which then thickens to form the fornix. Fimbria, Brain,Commissura Hippocampi,Commissure of Fornix,Dorsal Hippocampal Commissure,Fimbria (Brain),Fimbria of Hippocampus,Fimbria-Fornix,Fornical Commissure,Fornix (Brain),Fornix-Fimbria,Hippocampal Commissure,Brain Fimbria,Brain Fimbrias,Brain Fornices,Brain Fornix,Commissura Hippocampus,Commissure, Dorsal Hippocampal,Commissure, Fornical,Commissure, Hippocampal,Commissures, Dorsal Hippocampal,Commissures, Fornical,Commissures, Hippocampal,Dorsal Hippocampal Commissures,Fimbria Fornix,Fimbria-Fornices,Fimbrias (Brain),Fimbrias, Brain,Fornical Commissures,Fornices (Brain),Fornices, Brain,Fornix Commissure,Fornix Commissures,Fornix Fimbria,Fornix-Fimbrias,Hippocampal Commissure, Dorsal,Hippocampal Commissures,Hippocampal Commissures, Dorsal,Hippocampi, Commissura,Hippocampus Fimbria,Hippocampus Fimbrias,Hippocampus, Commissura

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