Atherosclerosis: Treating atherosclerosis with antitumour antibodies.
2016
Irene Fernández-Ruiz
UI
MeSH Term
Description
Entries
D010587
Phagocytosis
The engulfing and degradation of microorganisms; other cells that are dead, dying, or pathogenic; and foreign particles by phagocytic cells (PHAGOCYTES).
Phagocytoses
D006801
Humans
Members of the species Homo sapiens.
Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D050197
Atherosclerosis
A thickening and loss of elasticity of the walls of ARTERIES that occurs with formation of ATHEROSCLEROTIC PLAQUES within the ARTERIAL INTIMA.
Atherogenesis,Atherogeneses,Atheroscleroses
D051928
CD47 Antigen
A ubiquitously expressed membrane glycoprotein. It interacts with a variety of INTEGRINS and mediates responses to EXTRACELLULAR MATRIX PROTEINS.
Antigens, CD47,CD47 Antigens,IAP-50 Antigen,Integrin-Associated Protein p50,Thrombospondin-1 Receptor CD47,Antigen, CD47,Antigen, IAP-50,CD47, Thrombospondin-1 Receptor,IAP 50 Antigen,Integrin Associated Protein p50
D019138
Antibodies, Blocking
Antibodies that inhibit the reaction between ANTIGEN and other antibodies or sensitized T-LYMPHOCYTES (e.g., antibodies of the IMMUNOGLOBULIN G class that compete with IGE antibodies for antigen, thereby blocking an allergic response). Blocking antibodies that bind tumors and prevent destruction of tumor cells by CYTOTOXIC T-LYMPHOCYTES have also been called enhancing antibodies. (Rosen et al., Dictionary of Immunology, 1989)