Biomaterial Database

Platelet granules - secretory and secretive. 2017

Kerstin Jurk

PD Dr. rer. nat. Kerstin Jurk Center for Thrombosis and Hemostasis (CTH) University Medical Center Mainz Langenbeckstr. 1, 55131 Mainz, Germany E-Mail: kerstin.jurk@unimedizin-mainz.de.

The article reviews three recent publications addressing physiological and pathological aspects of platelet granules and release as well as limitations of recent screening tests for diagnosis of non-syndromic inherited δ-storage pool disease (1-3).

UI	MeSH Term	Description	Entries
D010981	Platelet Storage Pool Deficiency	Disorder characterized by a decrease or lack of platelet dense bodies in which the releasable pool of adenine nucleotides and 5HT are normally stored.	Storage Pool Deficiency,Acquired Storage Pool Disease,Deficiency, Platelet Storage Pool,Deficiency, Storage Pool,Familial Platelet Storage Pool Disease,Platelet Storage Pool Deficiencies,Platelet Storage Pool Disease,Storage Pool Deficiency, Platelet,Storage Pool Platelet Disease,Deficiencies, Storage Pool,Storage Pool Deficiencies
D001792	Blood Platelets	Non-nucleated disk-shaped cells formed in the megakaryocyte and found in the blood of all mammals. They are mainly involved in blood coagulation.	Platelets,Thrombocytes,Blood Platelet,Platelet,Platelet, Blood,Platelets, Blood,Thrombocyte
D003937	Diagnosis, Differential	Determination of which one of two or more diseases or conditions a patient is suffering from by systematically comparing and contrasting results of diagnostic measures.	Diagnoses, Differential,Differential Diagnoses,Differential Diagnosis
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D055652	Gray Platelet Syndrome	A rare, inherited platelet disorder characterized by a selective deficiency in the number and contents of platelet alpha-granules. It is associated with THROMBOCYTOPENIA, enlarged platelets, and prolonged bleeding time.	Grey Platelet Syndrome,Platelet alpha-Granule Deficiency,Gray Platelet Syndromes,Grey Platelet Syndromes,Platelet Syndromes, Grey,Platelet alpha Granule Deficiency,Platelet alpha-Granule Deficiencies,Syndrome, Gray Platelet,Syndrome, Grey Platelet,Syndromes, Gray Platelet,alpha-Granule Deficiencies, Platelet,alpha-Granule Deficiency, Platelet
D022142	Secretory Vesicles	Vesicles derived from the GOLGI APPARATUS containing material to be released at the cell surface.	SLMVs,Secretory Granules,Synaptic Like Microvesicles,Synaptic-Like Microvesicles,Zymogen Granules,Condensing Vacuoles,Condensing Vacuole,Granule, Secretory,Granule, Zymogen,Microvesicle, Synaptic-Like,Secretory Granule,Secretory Vesicle,Synaptic Like Microvesicle,Synaptic-Like Microvesicle,Vacuole, Condensing,Vesicle, Secretory,Zymogen Granule