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On the basis of neurological evidence that autistic patients have fewer Purkinje and granule cells in the cerebellum as well as vermal cerebellar hypoplasia, the authors tested the hypothesis that autistic patients have cerebellar hypofunctioning. They used positron emission tomography of the cerebellum with 18F-labeled 2-deoxyglucose to study seven autistic patients and eight age-matched control subjects. The results showed no significant difference in mean cerebellar glucose metabolism between the two groups, but all mean glucose rates of the autistic patients were either equal to or greater than those of the control subjects. The implications of these findings are discussed.
C W Heh, and
R Smith, and
J Wu, and
E Hazlett, and
A Russell, and
R Asarnow, and
P Tanguay, and
M S Buchsbaum
January 1993,
Revue neurologique,
C W Heh, and
R Smith, and
J Wu, and
E Hazlett, and
A Russell, and
R Asarnow, and
P Tanguay, and
M S Buchsbaum
November 1985,
Proceedings of the National Academy of Sciences of the United States of America,
C W Heh, and
R Smith, and
J Wu, and
E Hazlett, and
A Russell, and
R Asarnow, and
P Tanguay, and
M S Buchsbaum
January 2013,
Journal of thoracic imaging,
C W Heh, and
R Smith, and
J Wu, and
E Hazlett, and
A Russell, and
R Asarnow, and
P Tanguay, and
M S Buchsbaum
December 2002,
Journal de radiologie,
C W Heh, and
R Smith, and
J Wu, and
E Hazlett, and
A Russell, and
R Asarnow, and
P Tanguay, and
M S Buchsbaum
January 2022,
Frontiers in neuroscience,
C W Heh, and
R Smith, and
J Wu, and
E Hazlett, and
A Russell, and
R Asarnow, and
P Tanguay, and
M S Buchsbaum
September 2022,
Irish journal of psychological medicine,
C W Heh, and
R Smith, and
J Wu, and
E Hazlett, and
A Russell, and
R Asarnow, and
P Tanguay, and
M S Buchsbaum
November 2007,
Seminars in nuclear medicine,
C W Heh, and
R Smith, and
J Wu, and
E Hazlett, and
A Russell, and
R Asarnow, and
P Tanguay, and
M S Buchsbaum
March 2013,
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia,
C W Heh, and
R Smith, and
J Wu, and
E Hazlett, and
A Russell, and
R Asarnow, and
P Tanguay, and
M S Buchsbaum
July 2006,
Physics in medicine and biology,
C W Heh, and
R Smith, and
J Wu, and
E Hazlett, and
A Russell, and
R Asarnow, and
P Tanguay, and
M S Buchsbaum
May 1997,
Medizinische Monatsschrift fur Pharmazeuten,
