Biomaterial Database

IgA nephropathy: overproduction or decreased clearance of immune complexes? 1989

S N Emancipator, and M E Lamm

Institute of Pathology, Case Western Reserve University, Cleveland, Ohio.

UI	MeSH Term	Description	Entries
D007070	Immunoglobulin A	Represents 15-20% of the human serum immunoglobulins, mostly as the 4-chain polymer in humans or dimer in other mammals. Secretory IgA (IMMUNOGLOBULIN A, SECRETORY) is the main immunoglobulin in secretions.	IgA,IgA Antibody,IgA1,IgA2,Antibody, IgA
D009399	Nephrons	The functional units of the kidney, consisting of the glomerulus and the attached tubule.	Nephron
D010586	Phagocytes	Cells that can carry out the process of PHAGOCYTOSIS.	Phagocyte,Phagocytic Cell,Phagocytic Cells,Cell, Phagocytic,Cells, Phagocytic
D005922	Glomerulonephritis, IGA	A chronic form of glomerulonephritis characterized by deposits of predominantly IMMUNOGLOBULIN A in the mesangial area (GLOMERULAR MESANGIUM). Deposits of COMPLEMENT C3 and IMMUNOGLOBULIN G are also often found. Clinical features may progress from asymptomatic HEMATURIA to END-STAGE KIDNEY DISEASE.	Berger Disease,Immunoglobulin A Nephropathy,Nephropathy, IGA,Berger's Disease,IGA Glomerulonephritis,IGA Nephropathy,Iga Nephropathy 1,Nephritis, IGA Type,Bergers Disease,Glomerulonephritides, IGA,IGA Type Nephritis,Nephropathy 1, Iga,Nephropathy, Immunoglobulin A
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D000936	Antigen-Antibody Complex	The complex formed by the binding of antigen and antibody molecules. The deposition of large antigen-antibody complexes leading to tissue damage causes IMMUNE COMPLEX DISEASES.	Immune Complex,Antigen-Antibody Complexes,Immune Complexes,Antigen Antibody Complex,Antigen Antibody Complexes,Complex, Antigen-Antibody,Complex, Immune,Complexes, Antigen-Antibody,Complexes, Immune

Related Publications

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IgA nephropathy: clearance kinetics of IgA-containing immune complexes.

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Delayed clearance of specific polymeric IgA immune complexes in patients with IgA nephropathy.

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Immune complexes in IgA nephropathy: presence of antibodies against diet antigens and delayed clearance of specific polymeric IgA immune complexes.

October 1983, Clinical and experimental immunology,

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[Circulating immune complexes in IgA nephropathy].

September 1982, Nihon Jinzo Gakkai shi,

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Presence of specific IgA immune complexes in IgA nephropathy.

January 1984, Contributions to nephrology,

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Food antigens, IgA-immune complexes and IgA mesangial nephropathy.

January 1988, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association,

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Composition of IgA-containing circulating immune complexes in IgA nephropathy.

November 1988, American journal of kidney diseases : the official journal of the National Kidney Foundation,

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Immune complexes in IgA nephropathy (Berger's disease).

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Clearance kinetics and fate of mouse IgA immune complexes prepared with monomeric or dimeric IgA.

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IgA glycosylation and IgA immune complexes in the pathogenesis of IgA nephropathy.

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