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Acute effects of peripheral histamine administration on arginine-8-vasopressin and oxytocin levels in rat spinal cord. 1989
I Jójárt, and
M Vecsernyés, and
J Jójárt, and
F Laczi, and
G Szabó, and
G L Kovács, and
T Janáky, and
F A László, and
G Telegdy
First Department of Medicine, Albert Szent-Györgyi University Medical School, Szeged, Hungary.
The effects of a single injection of 20 mg/kg histamine on the immunoreactive arginine-8-vasopressin (AVP) and oxytocin (OXT) levels in the rat spinal cord were studied after peripheral (intraperitoneal) administration. Histamine induced a 60% elevation in the AVP content of the spinal cord, whereas the spinal level of OXT decreased by 36%. The findings suggest that peripheral histamine differentially affects the AVP and OXT levels in the spinal cord.
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