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Human gamma type interferon (IFN) preparations were obtained through phytohemagglutinin stimulation of leukocytes from the peripheral blood. Biological value of these preparations varied between 160 u and 800 u/ml, depending on leukocyte incubation medium, culture system and inductor conservation. The rising of the antiviral activity through association between gamma (3 u) and alpha (27 u) interferons was revealed by the virus quantity reduction (in this case the vesicular stomatitis virus was used) during a 24-hour multiplication cycle. The protection ensured by the mixture of the two types of interferon was about ten times higher than the additive effect of the two preparations. Study of the antiproliferative activity of a gamma interferon preparation was conducted on two human cell lines of tumoral origin (T-10 from a glioblastoma, and HEp-2) and revealed the difficulties to quantify precisely this property of the crude gamma interferon preparations.
G Danielescu, and
H Maniu, and
T Georgescu, and
N Cajal
November 1969,
Applied microbiology,
G Danielescu, and
H Maniu, and
T Georgescu, and
N Cajal
July 1965,
Science (New York, N.Y.),
G Danielescu, and
H Maniu, and
T Georgescu, and
N Cajal
July 1965,
Science (New York, N.Y.),
G Danielescu, and
H Maniu, and
T Georgescu, and
N Cajal
September 1981,
Journal of immunology (Baltimore, Md. : 1950),
G Danielescu, and
H Maniu, and
T Georgescu, and
N Cajal
March 1975,
Problemy gematologii i perelivaniia krovi,
G Danielescu, and
H Maniu, and
T Georgescu, and
N Cajal
November 1980,
European journal of immunology,
G Danielescu, and
H Maniu, and
T Georgescu, and
N Cajal
January 1983,
Voprosy virusologii,
G Danielescu, and
H Maniu, and
T Georgescu, and
N Cajal
July 1987,
The Journal of pediatrics,
G Danielescu, and
H Maniu, and
T Georgescu, and
N Cajal
December 1990,
Acta virologica,
G Danielescu, and
H Maniu, and
T Georgescu, and
N Cajal
January 1966,
Annales medicinae experimentalis et biologiae Fenniae,
