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A study in late 1979 to early 1980 was conducted to assess arbovirus activity in the Eastern Province of Saudi Arabia. From 38,245 mosquitoes collected at 3 locations, 16 isolations of Sindbis virus were made: 13 from Culex univittatus and one each from Cx tritaeniorhynchus, Cx pipiens complex, and Culex spp. These isolations represent the first records of a mosquito-borne virus from the Gulf of Arabia and implicate Cx univittatus as the principal vector. A potential risk of human diseases exists due to Sindbis virus in Saudi Arabia.
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