Non-O1 Vibrio cholerae produces two newly identified toxins related to Vibrio parahaemolyticus haemolysin and Escherichia coli heat-stable enterotoxin. 1985

T Honda, and M Arita, and T Takeda, and M Yoh, and T Miwatani

UI MeSH Term Description Entries
D002772 Cholera Toxin An ENTEROTOXIN from VIBRIO CHOLERAE. It consists of two major protomers, the heavy (H) or A subunit and the B protomer which consists of 5 light (L) or B subunits. The catalytic A subunit is proteolytically cleaved into fragments A1 and A2. The A1 fragment is a MONO(ADP-RIBOSE) TRANSFERASE. The B protomer binds cholera toxin to intestinal epithelial cells and facilitates the uptake of the A1 fragment. The A1 catalyzed transfer of ADP-RIBOSE to the alpha subunits of heterotrimeric G PROTEINS activates the production of CYCLIC AMP. Increased levels of cyclic AMP are thought to modulate release of fluid and electrolytes from intestinal crypt cells. Cholera Toxin A,Cholera Toxin B,Cholera Toxin Protomer A,Cholera Toxin Protomer B,Cholera Toxin Subunit A,Cholera Toxin Subunit B,Choleragen,Choleragenoid,Cholera Enterotoxin CT,Cholera Exotoxin,Cholera Toxin A Subunit,Cholera Toxin B Subunit,Procholeragenoid,Enterotoxin CT, Cholera,Exotoxin, Cholera,Toxin A, Cholera,Toxin B, Cholera,Toxin, Cholera
D004768 Enterotoxins Substances that are toxic to the intestinal tract causing vomiting, diarrhea, etc.; most common enterotoxins are produced by bacteria. Staphylococcal Enterotoxin,Enterotoxin,Staphylococcal Enterotoxins,Enterotoxin, Staphylococcal,Enterotoxins, Staphylococcal
D006358 Hot Temperature Presence of warmth or heat or a temperature notably higher than an accustomed norm. Heat,Hot Temperatures,Temperature, Hot,Temperatures, Hot
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D014734 Vibrio cholerae The etiologic agent of CHOLERA. Bacillus cholerae,Bacillus cholerae-asiaticae,Liquidivibrio cholerae,Microspira comma,Pacinia cholerae-asiaticae,Spirillum cholerae,Spirillum cholerae-asiaticae,Vibrio albensis,Vibrio cholera,Vibrio cholerae-asiaticae,Vibrio comma
D014736 Vibrio parahaemolyticus A species of bacteria found in the marine environment, sea foods, and the feces of patients with acute enteritis. Beneckea parahaemolytica,Oceanomonas parahaemolytica,Pasteurella parahaemolytica

Related Publications

T Honda, and M Arita, and T Takeda, and M Yoh, and T Miwatani
March 1995, FEMS microbiology letters,
T Honda, and M Arita, and T Takeda, and M Yoh, and T Miwatani
December 1990, Japanese journal of medical science & biology,
T Honda, and M Arita, and T Takeda, and M Yoh, and T Miwatani
January 2011, Proceedings of the Japan Academy. Series B, Physical and biological sciences,
T Honda, and M Arita, and T Takeda, and M Yoh, and T Miwatani
September 1983, Infection and immunity,
T Honda, and M Arita, and T Takeda, and M Yoh, and T Miwatani
July 1996, Journal of medical microbiology,
T Honda, and M Arita, and T Takeda, and M Yoh, and T Miwatani
April 2004, Emerging infectious diseases,
T Honda, and M Arita, and T Takeda, and M Yoh, and T Miwatani
May 1991, FEMS microbiology letters,
T Honda, and M Arita, and T Takeda, and M Yoh, and T Miwatani
August 1993, Lancet (London, England),
T Honda, and M Arita, and T Takeda, and M Yoh, and T Miwatani
April 1995, FEMS immunology and medical microbiology,
Copied contents to your clipboard!