BIOMAT Database Logo BIOMAT Database Logo

Cytomegaloviral hypophysitis in a simian immunodeficiency virus-infected rhesus macaque (Macacca mulatta). 2017

Melissa R Berg, and Michael A Owston, and Marie-Claire Gauduin, and Basel T Assaf, and Anne D Lewis, and Edward J Dick
Southwest National Primate Research Center at the Texas Biomedical Research Institute, San Antonio, TX, USA.

Rhesus macaques experimentally infected with Simian Immunodeficiency Virus (SIV) experience immunosuppression and often opportunistic infection. Among the most common opportunistic infections are rhesus cytomegalovirus (RhCMV), a ubiquitous betaherpesvirus that undergoes continuous low-level replication in immunocompetent monkeys. Upon SIV-mediated immunodeficiency, RhCMV reactivates and results in lesions in numerous organ systems including the nervous and reproductive systems. We report the first case of cytomegaloviral hypophysitis in a SIV-immunocompromised rhesus macaque.

UI MeSH Term Description Entries
D008253 Macaca mulatta A species of the genus MACACA inhabiting India, China, and other parts of Asia. The species is used extensively in biomedical research and adapts very well to living with humans. Chinese Rhesus Macaques,Macaca mulatta lasiota,Monkey, Rhesus,Rhesus Monkey,Rhesus Macaque,Chinese Rhesus Macaque,Macaca mulatta lasiotas,Macaque, Rhesus,Rhesus Macaque, Chinese,Rhesus Macaques,Rhesus Macaques, Chinese,Rhesus Monkeys
D009894 Opportunistic Infections An infection caused by an organism which becomes pathogenic under certain conditions, e.g., during immunosuppression. Infection, Opportunistic,Infections, Opportunistic,Opportunistic Infection
D003587 Cytomegalovirus A genus of the family HERPESVIRIDAE, subfamily BETAHERPESVIRINAE, infecting the salivary glands, liver, spleen, lungs, eyes, and other organs, in which they produce characteristically enlarged cells with intranuclear inclusions. Infection with Cytomegalovirus is also seen as an opportunistic infection in AIDS. Herpesvirus 5, Human,Human Herpesvirus 5,Salivary Gland Viruses,HHV 5,Herpesvirus 5 (beta), Human,Cytomegaloviruses,Salivary Gland Virus,Virus, Salivary Gland,Viruses, Salivary Gland
D005260 Female Females
D000072659 Hypophysitis Inflammation of the PITUITARY GLAND. Hypophysitides
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D015302 Simian Immunodeficiency Virus Species of the genus LENTIVIRUS, subgenus primate immunodeficiency viruses (IMMUNODEFICIENCY VIRUSES, PRIMATE), that induces acquired immunodeficiency syndrome in monkeys and apes (SAIDS). The genetic organization of SIV is virtually identical to HIV. SIV (Simian immunodeficiency virus),Immunodeficiency Viruses, Simian,Simian Immunodeficiency Viruses,Immunodeficiency Virus, Simian
D016097 Simian Acquired Immunodeficiency Syndrome Acquired defect of cellular immunity that occurs naturally in macaques infected with SRV serotypes, experimentally in monkeys inoculated with SRV or MASON-PFIZER MONKEY VIRUS; (MPMV), or in monkeys infected with SIMIAN IMMUNODEFICIENCY VIRUS. AIDS, Simian,SAIDS,Simian AIDS,Simian Acquired Immune Deficiency Syndrome,Simian Acquired Immuno-Deficiency Syndrome,AIDSs, Simian,Simian AIDSs,Simian Acquired Immuno Deficiency Syndrome
D016867 Immunocompromised Host A human or animal whose immunologic mechanism is deficient because of an immunodeficiency disorder or other disease or as the result of the administration of immunosuppressive drugs or radiation. Immunosuppressed Host,Immunocompromised Patient,Host, Immunocompromised,Host, Immunosuppressed,Hosts, Immunocompromised,Hosts, Immunosuppressed,Immunocompromised Hosts,Immunocompromised Patients,Immunosuppressed Hosts,Patient, Immunocompromised,Patients, Immunocompromised

Related Publications

Melissa R Berg, and Michael A Owston, and Marie-Claire Gauduin, and Basel T Assaf, and Anne D Lewis, and Edward J Dick
Dermatitis in a rhesus macaque (Macaca mulatta) experimentally infected with simian immunodeficiency virus.
February 2008, Journal of medical primatology,
Melissa R Berg, and Michael A Owston, and Marie-Claire Gauduin, and Basel T Assaf, and Anne D Lewis, and Edward J Dick
B-cell leukemia in a rhesus macaque (Macaca mulatta) infected with simian immunodeficiency virus.
May 2000, Leukemia & lymphoma,
Melissa R Berg, and Michael A Owston, and Marie-Claire Gauduin, and Basel T Assaf, and Anne D Lewis, and Edward J Dick
Persistent babesiosis in a Rhesus macaque (Macaca mulatta) infected with a simian-human immunodeficiency virus.
June 2014, Journal of medical primatology,
Melissa R Berg, and Michael A Owston, and Marie-Claire Gauduin, and Basel T Assaf, and Anne D Lewis, and Edward J Dick
Intestinal stromal tumors in a simian immunodeficiency virus-infected, simian retrovirus-2 negative rhesus macaque (Macaca mulatta).
May 2005, Veterinary pathology,
Melissa R Berg, and Michael A Owston, and Marie-Claire Gauduin, and Basel T Assaf, and Anne D Lewis, and Edward J Dick
Mesenchymoproliferative enteropathy associated with dual simian polyomavirus and rhesus cytomegalovirus infection in a simian immunodeficiency virus-infected rhesus macaque (Macaca mulatta).
July 2013, Veterinary pathology,
Melissa R Berg, and Michael A Owston, and Marie-Claire Gauduin, and Basel T Assaf, and Anne D Lewis, and Edward J Dick
Trichomonad gastritis in rhesus macaques (Macaca mulatta) infected with simian immunodeficiency virus.
January 2005, Veterinary pathology,
Melissa R Berg, and Michael A Owston, and Marie-Claire Gauduin, and Basel T Assaf, and Anne D Lewis, and Edward J Dick
Atypical nodular astrocytosis in simian immunodeficiency virus-infected rhesus macaques (Macaca mulatta).
December 2014, Journal of medical primatology,
Melissa R Berg, and Michael A Owston, and Marie-Claire Gauduin, and Basel T Assaf, and Anne D Lewis, and Edward J Dick
Microbial translocation in simian immunodeficiency virus (SIV)-infected rhesus monkeys (Macaca mulatta).
August 2010, Journal of medical primatology,
Melissa R Berg, and Michael A Owston, and Marie-Claire Gauduin, and Basel T Assaf, and Anne D Lewis, and Edward J Dick
Body-composition changes in the simian immunodeficiency virus-infected juvenile rhesus macaque.
June 2004, The Journal of infectious diseases,
Melissa R Berg, and Michael A Owston, and Marie-Claire Gauduin, and Basel T Assaf, and Anne D Lewis, and Edward J Dick
Hemophagocytic syndrome in a pancytopenic simian retrovirus-infected male rhesus macaque (Macaca mulatta).
November 2011, Veterinary pathology,
Copied contents to your clipboard!