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A case of AIDS due to HIV/LAV2 is reported. The patient was a 32 year old man from Guinea-Bissau with no known risk factors. He had brain toxoplasmosis, oral thrush and chronic genital herpes. Investigations for IgG anti-HIV/LAV1' (Elisa, Western Blot, Ripa) were negative. Antibodies to HIV/LAV2 were found and cultures of peripheral blood lymphocytes and cerebro-spinal fluid were positive. HIV/LAV2 seems to be similar to STLV-III (mac), STLV-III (agm), and probably HTLV-IV.
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