-transparent.png){kind=logo}
The susceptibilities of conventional and germ-free miniature pigs to staphylococcal toxic shock syndrome toxin 1 (TSST-1) were studied and compared. TSST-1 at doses of 100 micrograms/kg evoked reactions similar to those observed in rabbits, i.e., hyperthermia, diarrhea, apathy, conjunctival hyperemia, and various changes indicating toxic damage of different organs, but it was never lethal at this dose. Germ-free piglets were less susceptible than were corresponding conventional animals, a finding that may support the concept that endogenous endotoxin is involved in the pathogenesis of toxic shock syndrome.
Related Publications
M Bulanda, and
M Zaleska, and
L Mandel, and
M Talafantova, and
J Travnicek, and
G Kunstmann, and
G Mauff, and
G Pulverer, and
P B Heczko
November 1984,
Infection and immunity,
M Bulanda, and
M Zaleska, and
L Mandel, and
M Talafantova, and
J Travnicek, and
G Kunstmann, and
G Mauff, and
G Pulverer, and
P B Heczko
March 1986,
Journal of clinical microbiology,
M Bulanda, and
M Zaleska, and
L Mandel, and
M Talafantova, and
J Travnicek, and
G Kunstmann, and
G Mauff, and
G Pulverer, and
P B Heczko
January 1988,
Methods in enzymology,
M Bulanda, and
M Zaleska, and
L Mandel, and
M Talafantova, and
J Travnicek, and
G Kunstmann, and
G Mauff, and
G Pulverer, and
P B Heczko
January 2007,
Zhurnal mikrobiologii, epidemiologii i immunobiologii,
M Bulanda, and
M Zaleska, and
L Mandel, and
M Talafantova, and
J Travnicek, and
G Kunstmann, and
G Mauff, and
G Pulverer, and
P B Heczko
May 1999,
The Journal of allergy and clinical immunology,
M Bulanda, and
M Zaleska, and
L Mandel, and
M Talafantova, and
J Travnicek, and
G Kunstmann, and
G Mauff, and
G Pulverer, and
P B Heczko
March 1999,
Infection and immunity,
M Bulanda, and
M Zaleska, and
L Mandel, and
M Talafantova, and
J Travnicek, and
G Kunstmann, and
G Mauff, and
G Pulverer, and
P B Heczko
January 1989,
Reviews of infectious diseases,
M Bulanda, and
M Zaleska, and
L Mandel, and
M Talafantova, and
J Travnicek, and
G Kunstmann, and
G Mauff, and
G Pulverer, and
P B Heczko
October 1995,
Zentralblatt fur Bakteriologie : international journal of medical microbiology,
M Bulanda, and
M Zaleska, and
L Mandel, and
M Talafantova, and
J Travnicek, and
G Kunstmann, and
G Mauff, and
G Pulverer, and
P B Heczko
October 1993,
Journal of clinical microbiology,
M Bulanda, and
M Zaleska, and
L Mandel, and
M Talafantova, and
J Travnicek, and
G Kunstmann, and
G Mauff, and
G Pulverer, and
P B Heczko
December 1981,
The New England journal of medicine,
