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Markers and functions of T cell subsets were studied in 3 Israeli males suffering from AIDS, two of whom were homosexuals and one heterosexual developing AIDS after a coronary bypass operation followed by multiple blood transfusions. Two healthy homosexual partners of one of the AIDS patients were also studied. Sera from these individuals were also tested for suppressive activity on control normal donor lymphocytes. Monitoring of T-cell subsets during a period of 3-12 months demonstrated a reversed T helper: T suppressor ratio in the 3 AIDS patients and in one of the healthy homosexuals. Addition of AIDS sera to normal T helper cells abolished the helper activity whereas its addition to normal isolated T suppressor cells enhanced the suppressor activity. Incubation of the patients lymphocytes with THF, a calf thymus hormone, restored the impaired helper cell activity. A suppressor factor unrelated to acid labile interferon was demonstrated in the sera of the AIDS patients but was not found in the sera of the healthy homosexuals. THF neutralized the suppressor effect of this serum factor when tested on normal lymphocytes.
B Shohat, and
H Joshua, and
G Delpre, and
E Geller, and
I Blum, and
E Theodor, and
N Trainin
July 1983,
The New England journal of medicine,
B Shohat, and
H Joshua, and
G Delpre, and
E Geller, and
I Blum, and
E Theodor, and
N Trainin
December 1984,
Israel journal of medical sciences,
B Shohat, and
H Joshua, and
G Delpre, and
E Geller, and
I Blum, and
E Theodor, and
N Trainin
June 1986,
Archives of internal medicine,
B Shohat, and
H Joshua, and
G Delpre, and
E Geller, and
I Blum, and
E Theodor, and
N Trainin
January 2004,
African journal of health sciences,
B Shohat, and
H Joshua, and
G Delpre, and
E Geller, and
I Blum, and
E Theodor, and
N Trainin
October 1991,
Klinische Wochenschrift,
B Shohat, and
H Joshua, and
G Delpre, and
E Geller, and
I Blum, and
E Theodor, and
N Trainin
April 1983,
The New England journal of medicine,
B Shohat, and
H Joshua, and
G Delpre, and
E Geller, and
I Blum, and
E Theodor, and
N Trainin
May 1984,
Soins; la revue de reference infirmiere,
B Shohat, and
H Joshua, and
G Delpre, and
E Geller, and
I Blum, and
E Theodor, and
N Trainin
January 1984,
Srpski arhiv za celokupno lekarstvo,
B Shohat, and
H Joshua, and
G Delpre, and
E Geller, and
I Blum, and
E Theodor, and
N Trainin
May 1985,
Nederlands tijdschrift voor tandheelkunde,
B Shohat, and
H Joshua, and
G Delpre, and
E Geller, and
I Blum, and
E Theodor, and
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December 1985,
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