Efferent and afferent activity in a gastrocnemius nerve branch during locomotion in the thalamic cat. 1986

P Bessou, and J M Cabelguen, and M Joffroy, and R Montoya, and B Pagès

The firing patterns of alpha and gamma efferent fibres and of group I and group II afferent fibres innervating the gastrocnemius muscle were observed during spontaneous locomotor movements in the thalamic cat. Multi-unit discharges of each kind of fibre were obtained by electronic sorting of the action potentials from the whole activity of a thin branch of gastrocnemius lateralis or medialis nerve. The main results were: During the locomotor cycle the activity of the afferent and efferent populations was highly modulated. alpha- and gamma-motoneurones were co-activated within the locomotor cycle during ankle plantar-flexion. The gamma discharge began to rise earlier and to fall later than did the alpha discharge. The amplitude of the gamma discharge, unlike that of the alpha discharge, was largely independent of the vigour of walking. Between the cyclic discharges, most of gamma populations were tonically active whereas alpha populations were silent. Subgroups of the alpha and gamma populations were not usually activated according to the cell-size principle, but, the activation of the latest gamma subgroup always preceded that of the earliest alpha subgroup. Modulation of the group I and II afferent discharges was closely related to the cyclic length changes of the parent muscle. Fusimotor activation during the active shortening of gastrocnemius muscle prevented the afferent discharges from pausing. The pattern of afferent and efferent activity during selective curarisation of the extrafusal junctions indicated that the discharge of static gamma-motoneurones is modulated during the locomotor cycle. After curarisation of both extrafusal and intrafusal junctions, an efferent-discharge pattern of central origin persisted alternately in extensor- and flexor-muscle nerves (fictive locomotion). The durations of the fictive locomotor cycle and of the cyclic discharge in the sartorius nerve were increased as a consequence of the suppression of phasic afferent inputs to the C.N.S. Maintained ankle dorsi-flexion slowed the fictive locomotor rhythm and elicited opposite effects, respectively excitation and depression, on the magnitude of the alpha and gamma discharges. Maintained ankle plantar-flexion scarcely perturbed the duration of the fictive locomotor cycle, but the duration of the sartorius-nerve discharge lengthened at the expense of that of the gastrocnemius discharge. Both gastrocnemius alpha- and gamma-motoneurones were depressed, the former considerably more than the latter. The roles of the gastrocnemius afferents and gamma-efferents during the locomotor cycle are discussed in the light of these results.

UI MeSH Term Description Entries
D008124 Locomotion Movement or the ability to move from one place or another. It can refer to humans, vertebrate or invertebrate animals, and microorganisms. Locomotor Activity,Activities, Locomotor,Activity, Locomotor,Locomotor Activities
D009046 Motor Neurons Neurons which activate MUSCLE CELLS. Neurons, Motor,Alpha Motorneurons,Motoneurons,Motor Neurons, Alpha,Neurons, Alpha Motor,Alpha Motor Neuron,Alpha Motor Neurons,Alpha Motorneuron,Motoneuron,Motor Neuron,Motor Neuron, Alpha,Motorneuron, Alpha,Motorneurons, Alpha,Neuron, Alpha Motor,Neuron, Motor
D009047 Motor Neurons, Gamma Motor neurons which activate the contractile regions of intrafusal SKELETAL MUSCLE FIBERS, thus adjusting the sensitivity of the MUSCLE SPINDLES to stretch. Gamma motor neurons may be "static" or "dynamic" according to which aspect of responsiveness (or which fiber types) they regulate. The alpha and gamma motor neurons are often activated together (alpha gamma coactivation) which allows the spindles to contribute to the control of movement trajectories despite changes in muscle length. Neurons, Fusimotor,Neurons, Gamma Motor,Gamma Motorneurons,Motor Neurons, Gamma-Efferent,Fusimotor Neuron,Fusimotor Neurons,Gamma Motor Neuron,Gamma Motor Neurons,Gamma Motorneuron,Gamma-Efferent Motor Neuron,Gamma-Efferent Motor Neurons,Motor Neuron, Gamma,Motor Neuron, Gamma-Efferent,Motor Neurons, Gamma Efferent,Motorneuron, Gamma,Motorneurons, Gamma,Neuron, Fusimotor,Neuron, Gamma Motor,Neuron, Gamma-Efferent Motor,Neurons, Gamma-Efferent Motor
D009132 Muscles Contractile tissue that produces movement in animals. Muscle Tissue,Muscle,Muscle Tissues,Tissue, Muscle,Tissues, Muscle
D009470 Muscle Spindles Skeletal muscle structures that function as the MECHANORECEPTORS responsible for the stretch or myotactic reflex (REFLEX, STRETCH). They are composed of a bundle of encapsulated SKELETAL MUSCLE FIBERS, i.e., the intrafusal fibers (nuclear bag 1 fibers, nuclear bag 2 fibers, and nuclear chain fibers) innervated by SENSORY NEURONS. Muscle Stretch Receptors,Neuromuscular Spindles,Receptors, Stretch, Muscle,Stretch Receptors, Muscle,Muscle Spindle,Muscle Stretch Receptor,Neuromuscular Spindle,Receptor, Muscle Stretch,Receptors, Muscle Stretch,Spindle, Muscle,Spindle, Neuromuscular,Spindles, Muscle,Spindles, Neuromuscular,Stretch Receptor, Muscle
D010507 Periodicity The tendency of a phenomenon to recur at regular intervals; in biological systems, the recurrence of certain activities (including hormonal, cellular, neural) may be annual, seasonal, monthly, daily, or more frequently (ultradian). Cyclicity,Rhythmicity,Biological Rhythms,Bioperiodicity,Biorhythms,Biological Rhythm,Bioperiodicities,Biorhythm,Cyclicities,Periodicities,Rhythm, Biological,Rhythmicities,Rhythms, Biological
D002415 Cats The domestic cat, Felis catus, of the carnivore family FELIDAE, comprising over 30 different breeds. The domestic cat is descended primarily from the wild cat of Africa and extreme southwestern Asia. Though probably present in towns in Palestine as long ago as 7000 years, actual domestication occurred in Egypt about 4000 years ago. (From Walker's Mammals of the World, 6th ed, p801) Felis catus,Felis domesticus,Domestic Cats,Felis domestica,Felis sylvestris catus,Cat,Cat, Domestic,Cats, Domestic,Domestic Cat
D003655 Decerebrate State A condition characterized by abnormal posturing of the limbs that is associated with injury to the brainstem. This may occur as a clinical manifestation or induced experimentally in animals. The extensor reflexes are exaggerated leading to rigid extension of the limbs accompanied by hyperreflexia and opisthotonus. This condition is usually caused by lesions which occur in the region of the brainstem that lies between the red nuclei and the vestibular nuclei. In contrast, decorticate rigidity is characterized by flexion of the elbows and wrists with extension of the legs and feet. The causative lesion for this condition is located above the red nuclei and usually consists of diffuse cerebral damage. (From Adams et al., Principles of Neurology, 6th ed, p358) Decerebrate Posturing,Decorticate Rigidity,Decorticate State,Rigidity, Decerebrate,Rigidity, Decorticate,Decerebrate Posturings,Decerebrate Rigidity,Decerebrate States,Decorticate Rigidities,Decorticate States,Posturing, Decerebrate,Posturings, Decerebrate,Rigidities, Decorticate,State, Decerebrate,States, Decerebrate
D005528 Foot The distal extremity of the leg in vertebrates, consisting of the tarsus (ANKLE); METATARSUS; phalanges; and the soft tissues surrounding these bones. Feet
D006614 Hindlimb Either of two extremities of four-footed non-primate land animals. It usually consists of a FEMUR; TIBIA; and FIBULA; tarsals; METATARSALS; and TOES. (From Storer et al., General Zoology, 6th ed, p73) Hindlimbs

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