Numerical simulation of transapical off-pump mitral valve repair with neochordae implantation. 2018

Gediminas Gaidulis, and Emiliano Votta, and Matteo Selmi, and Sigita Aidietienė, and Audrius Aidietis, and Rimantas Kačianauskas
Department of Biomechanical Engineering, Vilnius Gediminas Technical University, Vilnius, Lithuania.

BACKGROUND Transapical off-pump mitral valve (MV) repair is a novel minimally-invasive surgical technique, allowing to correct mitral regurgitation (MR) caused by chordae tendineae rupture. While numerical simulation of the MV structure has proven to be useful to evaluate the effects of the MV surgical repair techniques, no numerical simulation studies on the outcomes of transapical MV repair have been done up to now. OBJECTIVE The purpose of this study is to evaluate the transapical MV repair using finite element modeling and to determine the effect of the neochordal length on the function of the prolapsing MV. METHODS The reconstruction of the MV geometry based on the patient-specific data was performed. In order to simulate prolapse, chordae inserted into the middle segment of the posterior leaflet (P2) were ruptured. A total of four virtual transapical repairs using neochordae of different length were performed. The function of the MV before and after virtual repairs was simulated. RESULTS The evaluation of the effect of the neochordal length on post-repair MV function showed that the length of the implanted neochordae has a significant impact on the correction of MR caused by chordae tendineae rupture. CONCLUSIONS The presented results can improve the understanding of the effects of transapical MV repair.

UI MeSH Term Description Entries
D008945 Mitral Valve Prolapse Abnormal protrusion or billowing of one or both of the leaflets of MITRAL VALVE into the LEFT ATRIUM during SYSTOLE. This allows the backflow of blood into left atrium leading to MITRAL VALVE INSUFFICIENCY; SYSTOLIC MURMURS; or CARDIAC ARRHYTHMIA. Floppy Mitral Valve,Mitral Click-Murmur Syndrome,Systolic Click-Murmur Syndrome,Click-Murmur Syndrome,Mitral Valve Prolapse Syndrome,Prolapsed Mitral Valve,Click Murmur Syndrome,Click-Murmur Syndrome, Mitral,Click-Murmur Syndrome, Systolic,Click-Murmur Syndromes,Floppy Mitral Valves,Mitral Click Murmur Syndrome,Mitral Valve Prolapses,Mitral Valve, Floppy,Mitral Valve, Prolapsed,Mitral Valves, Floppy,Mitral Valves, Prolapsed,Prolapse, Mitral Valve,Prolapsed Mitral Valves,Prolapses, Mitral Valve,Syndrome, Click-Murmur,Syndrome, Mitral Click-Murmur,Syndrome, Systolic Click-Murmur,Syndromes, Click-Murmur,Systolic Click Murmur Syndrome,Valve Prolapse, Mitral,Valve Prolapses, Mitral,Valve, Prolapsed Mitral,Valves, Prolapsed Mitral
D011474 Prosthesis Design The plan and delineation of prostheses in general or a specific prosthesis. Design, Prosthesis,Designs, Prosthesis,Prosthesis Designs
D004452 Echocardiography Ultrasonic recording of the size, motion, and composition of the heart and surrounding tissues. The standard approach is transthoracic. Echocardiography, Contrast,Echocardiography, Cross-Sectional,Echocardiography, M-Mode,Echocardiography, Transthoracic,Echocardiography, Two-Dimensional,Transthoracic Echocardiography,2-D Echocardiography,2D Echocardiography,Contrast Echocardiography,Cross-Sectional Echocardiography,Echocardiography, 2-D,Echocardiography, 2D,M-Mode Echocardiography,Two-Dimensional Echocardiography,2 D Echocardiography,Cross Sectional Echocardiography,Echocardiography, 2 D,Echocardiography, Cross Sectional,Echocardiography, M Mode,Echocardiography, Two Dimensional,M Mode Echocardiography,Two Dimensional Echocardiography
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000465 Algorithms A procedure consisting of a sequence of algebraic formulas and/or logical steps to calculate or determine a given task. Algorithm
D019060 Minimally Invasive Surgical Procedures Procedures that avoid use of open, invasive surgery in favor of closed or local surgery. These generally involve use of laparoscopic devices and remote-controlled manipulation of instruments with indirect observation of the surgical field through an endoscope or similar device. Minimal Access Surgical Procedures,Minimal Surgical Procedures,Minimally Invasive Surgical Procedure,Surgical Procedures, Minimally Invasive,Minimal Surgical Procedure,Minimally Invasive Surgery,Procedure, Minimal Surgical,Procedures, Minimal Access Surgical,Procedures, Minimal Surgical,Procedures, Minimally Invasive Surgical,Surgical Procedure, Minimal,Surgical Procedures, Minimal,Surgical Procedures, Minimal Access,Minimally Invasive Surgeries,Surgeries, Minimally Invasive,Surgery, Minimally Invasive
D020342 Finite Element Analysis A computer based method of simulating or analyzing the behavior of structures or components. Analysis, Finite Element,Analyses, Finite Element,Element Analyses, Finite,Element Analysis, Finite,Finite Element Analyses

Related Publications

Gediminas Gaidulis, and Emiliano Votta, and Matteo Selmi, and Sigita Aidietienė, and Audrius Aidietis, and Rimantas Kačianauskas
January 2021, Annals of cardiothoracic surgery,
Gediminas Gaidulis, and Emiliano Votta, and Matteo Selmi, and Sigita Aidietienė, and Audrius Aidietis, and Rimantas Kačianauskas
January 2023, Frontiers in cardiovascular medicine,
Gediminas Gaidulis, and Emiliano Votta, and Matteo Selmi, and Sigita Aidietienė, and Audrius Aidietis, and Rimantas Kačianauskas
March 2023, The Journal of thoracic and cardiovascular surgery,
Gediminas Gaidulis, and Emiliano Votta, and Matteo Selmi, and Sigita Aidietienė, and Audrius Aidietis, and Rimantas Kačianauskas
August 2018, The Annals of thoracic surgery,
Gediminas Gaidulis, and Emiliano Votta, and Matteo Selmi, and Sigita Aidietienė, and Audrius Aidietis, and Rimantas Kačianauskas
December 2016, Journal of cardiothoracic and vascular anesthesia,
Gediminas Gaidulis, and Emiliano Votta, and Matteo Selmi, and Sigita Aidietienė, and Audrius Aidietis, and Rimantas Kačianauskas
April 2021, Journal of cardiac surgery,
Gediminas Gaidulis, and Emiliano Votta, and Matteo Selmi, and Sigita Aidietienė, and Audrius Aidietis, and Rimantas Kačianauskas
December 2021, Revista portuguesa de cardiologia,
Gediminas Gaidulis, and Emiliano Votta, and Matteo Selmi, and Sigita Aidietienė, and Audrius Aidietis, and Rimantas Kačianauskas
February 2016, International journal of cardiology,
Gediminas Gaidulis, and Emiliano Votta, and Matteo Selmi, and Sigita Aidietienė, and Audrius Aidietis, and Rimantas Kačianauskas
September 2020, JTCVS open,
Gediminas Gaidulis, and Emiliano Votta, and Matteo Selmi, and Sigita Aidietienė, and Audrius Aidietis, and Rimantas Kačianauskas
April 2013, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery,
Copied contents to your clipboard!