Biomaterial Database

Mutagenicity of urine from greenhouse workers. 1988

B S Shane, and J M Scarlett-Kranz, and W S Reid, and D J Lisk

Institute for Environmental Studies, Louisiana State University, Baton Rouge.

The mutagenicity of urine from spray applicators in 12 greenhouses in 1986 has been evaluated. The workers served as their own controls. Urine samples reflecting pesticide exposure were collected at the end of the day of application and a corresponding control sample was collected 3 d later. Using Salmonella typhimurium bacterial tester strains TA98 and TA100 with and without S9 activation, seven workers showed no significant differences (p less than 0.05) in the mutagenicity of their exposed and control urine. Of the five remaining workers, three, who wore no respirators, showed significantly higher (p less than 0.05) concentrations of mutagens in their exposed urine sample as compared to their respective controls. The mutagenicity of certain of the compounds applied by these latter workers is discussed.

UI	MeSH Term	Description	Entries
D009152	Mutagenicity Tests	Tests of chemical substances and physical agents for mutagenic potential. They include microbial, insect, mammalian cell, and whole animal tests.	Genetic Toxicity Tests,Genotoxicity Tests,Mutagen Screening,Tests, Genetic Toxicity,Toxicity Tests, Genetic,Genetic Toxicity Test,Genotoxicity Test,Mutagen Screenings,Mutagenicity Test,Screening, Mutagen,Screenings, Mutagen,Test, Genotoxicity,Tests, Genotoxicity,Toxicity Test, Genetic
D009153	Mutagens	Chemical agents that increase the rate of genetic mutation by interfering with the function of nucleic acids. A clastogen is a specific mutagen that causes breaks in chromosomes.	Clastogen,Clastogens,Genotoxin,Genotoxins,Mutagen
D010575	Pesticides	Chemicals used to destroy pests of any sort. The concept includes fungicides (FUNGICIDES, INDUSTRIAL); INSECTICIDES; RODENTICIDES; etc.	Pesticide
D004781	Environmental Exposure	The exposure to potentially harmful chemical, physical, or biological agents in the environment or to environmental factors that may include ionizing radiation, pathogenic organisms, or toxic chemicals.	Exposure, Environmental,Environmental Exposures,Exposures, Environmental
D004784	Environmental Monitoring	The monitoring of the level of toxins, chemical pollutants, microbial contaminants, or other harmful substances in the environment (soil, air, and water), workplace, or in the bodies of people and animals present in that environment.	Monitoring, Environmental,Environmental Surveillance,Surveillance, Environmental
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000383	Agriculture	The science, art or practice of cultivating soil, producing crops, and raising livestock.	Agronomy,Agricultural Development,Farming,Agronomies,Development, Agricultural
D012486	Salmonella typhimurium	A serotype of Salmonella enterica that is a frequent agent of Salmonella gastroenteritis in humans. It also causes PARATYPHOID FEVER.	Salmonella typhimurium LT2