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At 8 and 32 hours after saphenous vein aortocoronary artery bypass graft surgery in four dogs, images of the grafts were obtained with a gamma camera after intravenous injection, 2 hours postoperatively, of autologous platelets labeled with indium-111. The location of platelet deposition could be accurately estimated from the scintiphotos. In vitro radioactivity counting of the segments of the isolated grafts showed 4 to 15 times greater activity in the grafts than in blood and 25 to 100 times greater activity than in normal myocardium. This was sufficient for delineating accurately the area of platelet deposition. This noninvasive technique may be a promising tool for a better understanding of the role played by platelets in the process of occlusion of saphenous vein bypass grafts in man.
M K Dewanjee, and
V Fuster, and
M P Kaye, and
M Josa
January 1986,
European journal of nuclear medicine,
M K Dewanjee, and
V Fuster, and
M P Kaye, and
M Josa
March 1985,
Mayo Clinic proceedings,
M K Dewanjee, and
V Fuster, and
M P Kaye, and
M Josa
April 1987,
Nuklearmedizin. Nuclear medicine,
M K Dewanjee, and
V Fuster, and
M P Kaye, and
M Josa
January 1987,
Radiology,
M K Dewanjee, and
V Fuster, and
M P Kaye, and
M Josa
January 1982,
European journal of nuclear medicine,
M K Dewanjee, and
V Fuster, and
M P Kaye, and
M Josa
October 1987,
Nihon Geka Gakkai zasshi,
M K Dewanjee, and
V Fuster, and
M P Kaye, and
M Josa
January 1993,
Acta radiologica (Stockholm, Sweden : 1987),
M K Dewanjee, and
V Fuster, and
M P Kaye, and
M Josa
May 2002,
The Annals of thoracic surgery,
M K Dewanjee, and
V Fuster, and
M P Kaye, and
M Josa
June 1997,
[Zasshi] [Journal]. Nihon Kyobu Geka Gakkai,
M K Dewanjee, and
V Fuster, and
M P Kaye, and
M Josa
January 1986,
Blood,
