[Acute renal failure of glomerular origin]. 2018

Éric Thervet
Service de néphrologie, département hypertension artérielle, prévention et prise en charge des affections rénales et cardiovasculaires, Hôpital européen Georges-Pompidou, Assistance publique-Hôpitaux de Paris, université Paris-Descartes Paris, France.

Acute renal failure of glomerular origin. Glomerulopathies account for about 10% of acute kidney injury (AKI) in adults. They often require urgent care. The clinico-biological presentations are acute nephritic syndrome (GNA) and rapidly progressive glomerulonephritis. GNA combines an organic AKI with signs of sodium retention. The most commonly found germs are streptococci, staphylococci and Escherichia coli. Rapidly progressive glomerulonephritis is characterized by a renal failure that settles in a few weeks, with marked hematuria. Blood tests depend of the context but include complement study and ANCA. Histologically, extracapillary lesions are present with various immunoglobulin deposits.

UI MeSH Term Description Entries
D005921 Glomerulonephritis Inflammation of the renal glomeruli (KIDNEY GLOMERULUS) that can be classified by the type of glomerular injuries including antibody deposition, complement activation, cellular proliferation, and glomerulosclerosis. These structural and functional abnormalities usually lead to HEMATURIA; PROTEINURIA; HYPERTENSION; and RENAL INSUFFICIENCY. Bright Disease,Kidney Scarring,Glomerulonephritides,Scarring, Kidney
D006417 Hematuria Presence of blood in the urine. Hematurias
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D058186 Acute Kidney Injury Abrupt reduction in kidney function. Acute kidney injury encompasses the entire spectrum of the syndrome including acute kidney failure; ACUTE KIDNEY TUBULAR NECROSIS; and other less severe conditions. Acute Kidney Failure,Acute Kidney Insufficiency,Acute Renal Failure,Acute Renal Injury,Acute Renal Insufficiency,Kidney Failure, Acute,Kidney Insufficiency, Acute,Renal Failure, Acute,Renal Insufficiency, Acute,Acute Kidney Failures,Acute Kidney Injuries,Acute Kidney Insufficiencies,Acute Renal Failures,Acute Renal Injuries,Acute Renal Insufficiencies,Kidney Failures, Acute,Kidney Injuries, Acute,Kidney Injury, Acute,Kidney Insufficiencies, Acute,Renal Failures, Acute,Renal Injuries, Acute,Renal Injury, Acute,Renal Insufficiencies, Acute

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