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A cDNA clone (HLUG 25) encoding the complete sequence of a human liver UDP-glucuronosyltransferase was isolated from a lambda gt11 human liver cDNA library. The library was screened by hybridization to a partial-length human UDP-glucuronosyltransferase cDNA (pHUDPGT1) identified from a human liver pEX cDNA expression library by using anti-UDP-glucuronosyltransferase antibodies. The authenticity of the cDNA clone was confirmed by hybrid-select translation and extensive sequence homology to rat liver UDP-glucuronosyltransferase cDNAs. The sequence of HLUG 25 cDNA was determined to be 2104 base-pairs long, including a poly(A) tail, and contains a long open reading frame. The possible site of translation initiation of this sequence is discussed with reference to a rat UDP-glucuronosyltransferase cDNA clone (RLUG 38).
M R Jackson, and
L R McCarthy, and
D Harding, and
S Wilson, and
M W Coughtrie, and
B Burchell
October 1997,
Archives of pharmacal research,
M R Jackson, and
L R McCarthy, and
D Harding, and
S Wilson, and
M W Coughtrie, and
B Burchell
August 1996,
Biochemical and biophysical research communications,
M R Jackson, and
L R McCarthy, and
D Harding, and
S Wilson, and
M W Coughtrie, and
B Burchell
July 1993,
Biochemical and biophysical research communications,
M R Jackson, and
L R McCarthy, and
D Harding, and
S Wilson, and
M W Coughtrie, and
B Burchell
March 2001,
Life sciences,
M R Jackson, and
L R McCarthy, and
D Harding, and
S Wilson, and
M W Coughtrie, and
B Burchell
September 1991,
The Biochemical journal,
M R Jackson, and
L R McCarthy, and
D Harding, and
S Wilson, and
M W Coughtrie, and
B Burchell
June 1995,
Molecular pharmacology,
M R Jackson, and
L R McCarthy, and
D Harding, and
S Wilson, and
M W Coughtrie, and
B Burchell
February 1977,
The Journal of biological chemistry,
M R Jackson, and
L R McCarthy, and
D Harding, and
S Wilson, and
M W Coughtrie, and
B Burchell
June 1999,
The Biochemical journal,
M R Jackson, and
L R McCarthy, and
D Harding, and
S Wilson, and
M W Coughtrie, and
B Burchell
January 1994,
Life sciences,
M R Jackson, and
L R McCarthy, and
D Harding, and
S Wilson, and
M W Coughtrie, and
B Burchell
August 1998,
Archives of biochemistry and biophysics,
