Urinary beta-1-galactosyl-0-hydroxylysine (GH) as a marker of collagen turnover of bone. 1988

L Moro, and R S Pozzi Mucelli, and C Gazzarrini, and C Modricky, and F Marotti, and B de Bernard
Dipartimento di Biochimica, Biofisica e Chimica delle Macromolecole, Trieste, Italy.

beta-1-galactosyl-0-hydroxylysine (GH) was measured in the urine of 59 women and 48 men, aged 30-79 years, by High Performance Liquid Chromatography (HPLC) of the dansylated derivative. Vertebral mineral density, measured by quantitative computed tomography (QCT), and urinary GH were inversely correlated (r = -0.74; P less than 0.001). High rate of bone mineral loss is associated with a high urinary GH excretion. Measurement of GH in urine provides a simple and noninvasive method for the evaluation of the extent of bone resorption in large groups of subjects and appears to be more specific than urinary hydroxyproline excretion.

UI MeSH Term Description Entries
D008297 Male Males
D008593 Menopause The last menstrual period. Permanent cessation of menses (MENSTRUATION) is usually defined after 6 to 12 months of AMENORRHEA in a woman over 45 years of age. In the United States, menopause generally occurs in women between 48 and 55 years of age. Change of Life, Female
D008903 Minerals Native, inorganic or fossilized organic substances having a definite chemical composition and formed by inorganic reactions. They may occur as individual crystals or may be disseminated in some other mineral or rock. (Grant & Hackh's Chemical Dictionary, 5th ed; McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) Mineral
D012016 Reference Values The range or frequency distribution of a measurement in a population (of organisms, organs or things) that has not been selected for the presence of disease or abnormality. Normal Range,Normal Values,Reference Ranges,Normal Ranges,Normal Value,Range, Normal,Range, Reference,Ranges, Normal,Ranges, Reference,Reference Range,Reference Value,Value, Normal,Value, Reference,Values, Normal,Values, Reference
D001842 Bone and Bones A specialized CONNECTIVE TISSUE that is the main constituent of the SKELETON. The principal cellular component of bone is comprised of OSTEOBLASTS; OSTEOCYTES; and OSTEOCLASTS, while FIBRILLAR COLLAGENS and hydroxyapatite crystals form the BONE MATRIX. Bone Tissue,Bone and Bone,Bone,Bones,Bones and Bone,Bones and Bone Tissue,Bony Apophyses,Bony Apophysis,Condyle,Apophyses, Bony,Apophysis, Bony,Bone Tissues,Condyles,Tissue, Bone,Tissues, Bone
D002940 Circadian Rhythm The regular recurrence, in cycles of about 24 hours, of biological processes or activities, such as sensitivity to drugs or environmental and physiological stimuli. Diurnal Rhythm,Nyctohemeral Rhythm,Twenty-Four Hour Rhythm,Nycthemeral Rhythm,Circadian Rhythms,Diurnal Rhythms,Nycthemeral Rhythms,Nyctohemeral Rhythms,Rhythm, Circadian,Rhythm, Diurnal,Rhythm, Nycthemeral,Rhythm, Nyctohemeral,Rhythm, Twenty-Four Hour,Rhythms, Circadian,Rhythms, Diurnal,Rhythms, Nycthemeral,Rhythms, Nyctohemeral,Rhythms, Twenty-Four Hour,Twenty Four Hour Rhythm,Twenty-Four Hour Rhythms
D003094 Collagen A polypeptide substance comprising about one third of the total protein in mammalian organisms. It is the main constituent of SKIN; CONNECTIVE TISSUE; and the organic substance of bones (BONE AND BONES) and teeth (TOOTH). Avicon,Avitene,Collagen Felt,Collagen Fleece,Collagenfleece,Collastat,Dermodress,Microfibril Collagen Hemostat,Pangen,Zyderm,alpha-Collagen,Collagen Hemostat, Microfibril,alpha Collagen
D003404 Creatinine Creatinine Sulfate Salt,Krebiozen,Salt, Creatinine Sulfate,Sulfate Salt, Creatinine
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man

Related Publications

L Moro, and R S Pozzi Mucelli, and C Gazzarrini, and C Modricky, and F Marotti, and B de Bernard
May 1999, Clinical chemistry,
L Moro, and R S Pozzi Mucelli, and C Gazzarrini, and C Modricky, and F Marotti, and B de Bernard
May 1989, Journal of chromatography,
L Moro, and R S Pozzi Mucelli, and C Gazzarrini, and C Modricky, and F Marotti, and B de Bernard
August 1999, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research,
L Moro, and R S Pozzi Mucelli, and C Gazzarrini, and C Modricky, and F Marotti, and B de Bernard
April 1995, The Journal of clinical endocrinology and metabolism,
L Moro, and R S Pozzi Mucelli, and C Gazzarrini, and C Modricky, and F Marotti, and B de Bernard
June 1996, FEBS letters,
L Moro, and R S Pozzi Mucelli, and C Gazzarrini, and C Modricky, and F Marotti, and B de Bernard
January 1995, Clinica chimica acta; international journal of clinical chemistry,
L Moro, and R S Pozzi Mucelli, and C Gazzarrini, and C Modricky, and F Marotti, and B de Bernard
August 1992, Acta paediatrica (Oslo, Norway : 1992),
L Moro, and R S Pozzi Mucelli, and C Gazzarrini, and C Modricky, and F Marotti, and B de Bernard
May 1977, Wiadomosci lekarskie (Warsaw, Poland : 1960),
L Moro, and R S Pozzi Mucelli, and C Gazzarrini, and C Modricky, and F Marotti, and B de Bernard
January 1994, Calcified tissue international,
L Moro, and R S Pozzi Mucelli, and C Gazzarrini, and C Modricky, and F Marotti, and B de Bernard
March 2006, The Journal of organic chemistry,
Copied contents to your clipboard!