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The in vitro effect of a calf thymus extract (TP-1) on peripheral blood lymphocytes was evaluated in sixty-six melanoma patients. Twenty out of forty-five stage I and seventeen out of twenty-one stage IIb patients presented depressed T lymphocyte values. A statistically significant increase in E-rosette-forming cells (E-RFC) was observed in seventeen (85%) stage I and twelve (70.5%) stage II patients. In thirteen (65%) stage I and eight (47%) stage II patients E-RFC reached normal values. Our results indicate that the fall of T lymphocytes in the peripheral blood of melanoma patients is often related to an increase in TP-1 sensitive cells which suggests the possibility of a thymic hormone deficiency in these patients.
M G Bernengo, and
G Capella, and
A de Matteis, and
P A Tovo, and
G Zina
January 1971,
Folia morphologica,
M G Bernengo, and
G Capella, and
A de Matteis, and
P A Tovo, and
G Zina
October 1982,
American journal of reproductive immunology : AJRI : official journal of the American Society for the Immunology of Reproduction and the International Coordination Committee for Immunology of Reproduction,
M G Bernengo, and
G Capella, and
A de Matteis, and
P A Tovo, and
G Zina
January 1977,
Patologia polska,
M G Bernengo, and
G Capella, and
A de Matteis, and
P A Tovo, and
G Zina
January 1980,
Cellular and molecular biology, including cyto-enzymology,
M G Bernengo, and
G Capella, and
A de Matteis, and
P A Tovo, and
G Zina
January 1975,
Bollettino dell'Istituto sieroterapico milanese,
M G Bernengo, and
G Capella, and
A de Matteis, and
P A Tovo, and
G Zina
January 1982,
Cancer,
M G Bernengo, and
G Capella, and
A de Matteis, and
P A Tovo, and
G Zina
June 1977,
Haematologica,
M G Bernengo, and
G Capella, and
A de Matteis, and
P A Tovo, and
G Zina
February 1974,
Infection and immunity,
M G Bernengo, and
G Capella, and
A de Matteis, and
P A Tovo, and
G Zina
January 1976,
Przeglad lekarski,
M G Bernengo, and
G Capella, and
A de Matteis, and
P A Tovo, and
G Zina
January 1977,
Voprosy onkologii,
