-transparent.png){kind=logo}
Peripheral blood lymphocytes from twenty patients with progressive systemic sclerosis (PSS) were analysed for the numbers and proportions of B lymphocytes possessing surface immunoglobulin, cells with Fc receptors, T cella and T cells with receptors for IgM (T mu) or IgG (T gamma). In patients with PSS, B cells and lymphocytes with Fc receptors were comparable in both numbers and proportions to those of the control group. Circulating T lymphocytes were significantly fewer in the patient group. T mu cells were decreased and T gamma cells increased, resulting in lower T mu/T gamma ratios as compared to controls. This study demonstrates a profound imbalance between T mu and T gamma cells (containing a population of helper or suppressor cells, respectively). These results are discussed in relation to immunodeficiencies observed in patients with PSS.
S Gupta, and
A N Malaviya, and
P Rajagopalan, and
R A Good
April 1991,
The Journal of allergy and clinical immunology,
S Gupta, and
A N Malaviya, and
P Rajagopalan, and
R A Good
January 1982,
Archives of dermatological research,
S Gupta, and
A N Malaviya, and
P Rajagopalan, and
R A Good
July 1983,
Arthritis and rheumatism,
S Gupta, and
A N Malaviya, and
P Rajagopalan, and
R A Good
January 1981,
Gerontology,
S Gupta, and
A N Malaviya, and
P Rajagopalan, and
R A Good
September 1975,
The Journal of rheumatology,
S Gupta, and
A N Malaviya, and
P Rajagopalan, and
R A Good
January 1985,
Acta medica Hungarica,
S Gupta, and
A N Malaviya, and
P Rajagopalan, and
R A Good
January 1993,
Rheumatology international,
S Gupta, and
A N Malaviya, and
P Rajagopalan, and
R A Good
January 1980,
International archives of allergy and applied immunology,
S Gupta, and
A N Malaviya, and
P Rajagopalan, and
R A Good
July 1980,
Immunology today,
S Gupta, and
A N Malaviya, and
P Rajagopalan, and
R A Good
August 1987,
Clinical and experimental immunology,
