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[Acute renal failure secondary to DRESS syndrome]. 2019

Elnaz Rahbari, and Roberto Cardillo, and Lucia Dimora, and Rosaria Gangemi, and Patrizia Boemi, and Rosaria Saitta, and Alessandro Cardillo, and Giovanni Rapisarda
Dipartimento di Medicina, sez di Nefrologia, Azienda Ospedalieri G.Rodolico, via Santa Sofia 86,95123 , Catania, Italia.

We report here the case of a 63-year-old man, diagnosed with rheumatoid arthritis, who presented fever, weakness, diarrhea, chest, limbs and face erythema 20 days after starting of therapy with salazopyrin; these symptoms only partially and temporarily subsided after early drug withdrawal. The subsequent intake of mesalazine during acute colitis, after 48 hours, determined a sever relapse characterized by high fever, general malaise, diffuse morbilliform rash on the trunk, face and limbs with visceral involvement (acute renal and hepatic injury). At this time the diagnosis of "Drug reaction with eosinophilia and systemic symptoms", or DRESS, was done according to "Regiscar" criteria. Mesalazine was therefore suspended and steroid therapy begun, inducing a slow but complete remission within two months.

UI MeSH Term Description Entries
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D058186 Acute Kidney Injury Abrupt reduction in kidney function. Acute kidney injury encompasses the entire spectrum of the syndrome including acute kidney failure; ACUTE KIDNEY TUBULAR NECROSIS; and other less severe conditions. Acute Kidney Failure,Acute Kidney Insufficiency,Acute Renal Failure,Acute Renal Injury,Acute Renal Insufficiency,Kidney Failure, Acute,Kidney Insufficiency, Acute,Renal Failure, Acute,Renal Insufficiency, Acute,Acute Kidney Failures,Acute Kidney Injuries,Acute Kidney Insufficiencies,Acute Renal Failures,Acute Renal Injuries,Acute Renal Insufficiencies,Kidney Failures, Acute,Kidney Injuries, Acute,Kidney Injury, Acute,Kidney Insufficiencies, Acute,Renal Failures, Acute,Renal Injuries, Acute,Renal Injury, Acute,Renal Insufficiencies, Acute
D063926 Drug Hypersensitivity Syndrome Severe drug eruption characterized by high fever, erythematous rash and inflammation of internal organ(s). Drug Reaction With Eosinophilia And Systemic Symptom,DRESS Syndrome,Drug Reaction with Eosinophilia and Systemic Symptoms,Drug Reaction with Eosinophilia and Systemic Symptoms Syndrome,DRESS Syndromes,Drug Hypersensitivity Syndromes,Hypersensitivity Syndrome, Drug,Hypersensitivity Syndromes, Drug,Syndrome, Drug Hypersensitivity,Syndromes, Drug Hypersensitivity

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