Biomaterial Database

DRESS syndrome secondary to carbamazepine. 2023

Miryam Moreta Rodríguez, and Félix García-Pajares, and Carolina Almohalla-Álvarez, and Carmen Alonso-Martín, and Antonio González López, and José Pablo Miramontes-González, and Javier Miguel Martín Guerra, and Begoña Morejón Huerta

Gastroenterología, Hospital Universitario Río Hortega, España.

DRESS syndrome is a multisystem disorder that appears in the context of an adverse drug reaction, characterized by fever, rash and peripheral eosinophilia with involvement of other organs such as the liver. The typical liver involvement is acute toxic hepatitis (DILI), showing improvement and a tendency to resolution when corticotherapy is started. We must not forget this manifestation in the clinical context of a DRESS syndrome.

UI	MeSH Term	Description	Entries
D002220	Carbamazepine	A dibenzazepine that acts as a sodium channel blocker. It is used as an anticonvulsant for the treatment of grand mal and psychomotor or focal SEIZURES. It may also be used in the management of BIPOLAR DISORDER, and has analgesic properties.	Amizepine,Carbamazepine Acetate,Carbamazepine Anhydrous,Carbamazepine Dihydrate,Carbamazepine Hydrochloride,Carbamazepine L-Tartrate (4:1),Carbamazepine Phosphate,Carbamazepine Sulfate (2:1),Carbazepin,Epitol,Finlepsin,Neurotol,Tegretol
D004802	Eosinophilia	Abnormal increase of EOSINOPHILS in the blood, tissues or organs.	Eosinophilia, Tropical,Hypereosinophilia,Tropical Eosinophilia,Hypereosinophilias,Tropical Eosinophilias
D005076	Exanthema	Diseases in which skin eruptions or rashes are a prominent manifestation. Classically, six such diseases were described with similar rashes; they were numbered in the order in which they were reported. Only the fourth (Duke's disease), fifth (ERYTHEMA INFECTIOSUM), and sixth (EXANTHEMA SUBITUM) numeric designations survive as occasional synonyms in current terminology.	Rash,Skin Rash,Exanthem,Rash, Skin
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000927	Anticonvulsants	Drugs used to prevent SEIZURES or reduce their severity.	Anticonvulsant,Anticonvulsant Drug,Anticonvulsive Agent,Anticonvulsive Drug,Antiepileptic,Antiepileptic Agent,Antiepileptic Agents,Antiepileptic Drug,Anticonvulsant Drugs,Anticonvulsive Agents,Anticonvulsive Drugs,Antiepileptic Drugs,Antiepileptics,Agent, Anticonvulsive,Agent, Antiepileptic,Agents, Anticonvulsive,Agents, Antiepileptic,Drug, Anticonvulsant,Drug, Anticonvulsive,Drug, Antiepileptic,Drugs, Anticonvulsant,Drugs, Anticonvulsive,Drugs, Antiepileptic
D001569	Benzodiazepines	A group of two-ring heterocyclic compounds consisting of a benzene ring fused to a diazepine ring.	Benzodiazepine,Benzodiazepine Compounds
D063926	Drug Hypersensitivity Syndrome	Severe drug eruption characterized by high fever, erythematous rash and inflammation of internal organ(s).	Drug Reaction With Eosinophilia And Systemic Symptom,DRESS Syndrome,Drug Reaction with Eosinophilia and Systemic Symptoms,Drug Reaction with Eosinophilia and Systemic Symptoms Syndrome,DRESS Syndromes,Drug Hypersensitivity Syndromes,Hypersensitivity Syndrome, Drug,Hypersensitivity Syndromes, Drug,Syndrome, Drug Hypersensitivity,Syndromes, Drug Hypersensitivity