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In a series of experiments on 230 noninbred white rats the trend in the development of soft tissue abscess was investigated under stimulation and inhibition of phagocytizing mononuclear cells (PMC). The results suggest the stimulation to promote more reliable localization of the inflammation focus and encapsulation with connective tissue. The test for alpha-naphthyl esterase and quantitation of macrophages (absolute number) per infiltration area unit adjacent to the abscess suggest a direct correlation between the absolute number of macrophages and the width of the capsule. The data obtained confirm the assumptions on the role of macrophages in inflammation focus as a regulatory and controlling factor for cellular reactions. PMC system is shown to affect the process of abscess separation from adjacent tissues including formation of the capsule.
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September 1986,
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Eksperimental'naia i klinicheskaia farmakologiia,
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Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association,
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Zhurnal mikrobiologii, epidemiologii i immunobiologii,
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D Safuan, and
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N G Ermakova
April 2017,
Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology,
D Safuan, and
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N G Ermakova
March 1985,
Tsitologiia,
