-transparent.png){kind=logo}
Human coagulation factor XII (fXII), a serine protease synthesized in liver and active in plasma, is involved in a wide variety of functions, including blood coagulation, fibrinolysis, bradykinin and complement activation. A complementary DNA (597 bp) encoding amino acid -16 to amino acid 183 of fXII protein was used to determine the chromosomal location of the fXII gene. DNAs from hamster-human somatic cell hybrids were digested with restriction enzymes and hybridized with the fXII cDNA. By the Southern method it was shown that restriction fragments able to hybridize to fXII cDNA are present only in DNA extracted from clones retaining human chromosome 5.
Related Publications
F Citarella, and
M Tripodi, and
A Fantoni, and
F Bernardi, and
G Romeo, and
M Rocchi
January 2001,
Cytogenetics and cell genetics,
F Citarella, and
M Tripodi, and
A Fantoni, and
F Bernardi, and
G Romeo, and
M Rocchi
January 1998,
Cytogenetics and cell genetics,
F Citarella, and
M Tripodi, and
A Fantoni, and
F Bernardi, and
G Romeo, and
M Rocchi
January 1993,
BioTechniques,
F Citarella, and
M Tripodi, and
A Fantoni, and
F Bernardi, and
G Romeo, and
M Rocchi
January 1978,
Cytogenetics and cell genetics,
F Citarella, and
M Tripodi, and
A Fantoni, and
F Bernardi, and
G Romeo, and
M Rocchi
January 1998,
Cytogenetics and cell genetics,
F Citarella, and
M Tripodi, and
A Fantoni, and
F Bernardi, and
G Romeo, and
M Rocchi
January 1990,
Cytogenetics and cell genetics,
F Citarella, and
M Tripodi, and
A Fantoni, and
F Bernardi, and
G Romeo, and
M Rocchi
January 1996,
Cytogenetics and cell genetics,
F Citarella, and
M Tripodi, and
A Fantoni, and
F Bernardi, and
G Romeo, and
M Rocchi
January 1997,
Cytogenetics and cell genetics,
F Citarella, and
M Tripodi, and
A Fantoni, and
F Bernardi, and
G Romeo, and
M Rocchi
February 2008,
Journal of thrombosis and haemostasis : JTH,
F Citarella, and
M Tripodi, and
A Fantoni, and
F Bernardi, and
G Romeo, and
M Rocchi
January 1980,
Cytogenetics and cell genetics,
