Biomaterial Database

[Perioperative treatment of patients with varicose veins using calcium dobesilate]. 1988

J Mühleder, and W Ohner, and S Duma

Abteilung für Chirurgie, des a. ö. Krankenhauses Krems a. d. Donau.

Altogether 120 patients with medium to serious forms of varicositas were examined perioperatively after having been divided into 3 groups. Groups I and II were administered perioperatively a daily dosage of 1000 mg (2 x 1 capsule) of the preparation Doxium (Ebewe Arzneimittel GmbH, Unterach am Attersee) during 8 weeks - 2 weeks preoperatively and 6 weeks postoperatively. Group III was used for control purposes. The following was valued as parameter of comparison: kind and seriousness of perioperative trouble, alteration of peripheric oedemas, results of plethysmographic examinations as well as light-reflex-rheography examinations and the post-operative healing-process. Groups I and II (medication of Doxium) showed a significant (p less than 0.05) reduction of the peripheric oedemas already in the preoperative state and postoperatively, the patients had less trouble and a quicker healing-process was observed compared with group III.

UI	MeSH Term	Description	Entries
D008209	Lymphedema	Edema due to obstruction of lymph vessels or disorders of the lymph nodes.	Milroy's Disease,Congenital Familial Lymphedema,Congenital Hereditary Lymphedema,Early Onset Lymphedema,Hereditary Lymphedema,Hereditary Lymphedema 1,Hereditary Lymphedema Type I,Lymphedema, Early-Onset,Lymphedema, Hereditary, Ia,Milroy Disease,Nonne-Milroy Disease,Nonne-Milroy Lymphedema,Nonne-Milroy-Meige Disease,Primary Congenital Lymphedema,Congenital Hereditary Lymphedemas,Congenital Lymphedema, Primary,Congenital Lymphedemas, Primary,Early Onset Lymphedemas,Early-Onset Lymphedema,Early-Onset Lymphedemas,Hereditary Lymphedema 1s,Hereditary Lymphedema, Congenital,Hereditary Lymphedemas,Hereditary Lymphedemas, Congenital,Lymphedema, Congenital Hereditary,Lymphedema, Early Onset,Lymphedema, Hereditary,Lymphedema, Nonne-Milroy,Lymphedema, Primary Congenital,Lymphedemas,Lymphedemas, Congenital Hereditary,Lymphedemas, Early Onset,Lymphedemas, Early-Onset,Lymphedemas, Hereditary,Lymphedemas, Primary Congenital,Milroys Disease,Nonne Milroy Disease,Nonne Milroy Lymphedema,Nonne Milroy Meige Disease,Primary Congenital Lymphedemas
D008297	Male		Males
D011183	Postoperative Complications	Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.	Complication, Postoperative,Complications, Postoperative,Postoperative Complication
D011292	Premedication	Preliminary administration of a drug preceding a diagnostic, therapeutic, or surgical procedure. The commonest types of premedication are antibiotics (ANTIBIOTIC PROPHYLAXIS) and anti-anxiety agents. It does not include PREANESTHETIC MEDICATION.	Premedications
D002123	Calcium Dobesilate	A drug used to reduce hemorrhage in diabetic retinopathy.	Dobesilate Calcium,2,5-Dihydroxybenzenesulfonate,2,5-Dihydroxybenzenesulfonic Acid,Calcium Dobesilate (1:1),Calcium Dobesilate Monoammonium Salt,Calcium Dobesilate Monopotassium Salt,Dexium,Dobica,Doxium,2,5 Dihydroxybenzenesulfonate,2,5 Dihydroxybenzenesulfonic Acid,Calcium, Dobesilate,Dobesilate, Calcium
D002199	Capillary Permeability	The property of blood capillary ENDOTHELIUM that allows for the selective exchange of substances between the blood and surrounding tissues and through membranous barriers such as the BLOOD-AIR BARRIER; BLOOD-AQUEOUS BARRIER; BLOOD-BRAIN BARRIER; BLOOD-NERVE BARRIER; BLOOD-RETINAL BARRIER; and BLOOD-TESTIS BARRIER. Small lipid-soluble molecules such as carbon dioxide and oxygen move freely by diffusion. Water and water-soluble molecules cannot pass through the endothelial walls and are dependent on microscopic pores. These pores show narrow areas (TIGHT JUNCTIONS) which may limit large molecule movement.	Microvascular Permeability,Permeability, Capillary,Permeability, Microvascular,Vascular Permeability,Capillary Permeabilities,Microvascular Permeabilities,Permeabilities, Capillary,Permeabilities, Microvascular,Permeabilities, Vascular,Permeability, Vascular,Vascular Permeabilities
D005260	Female		Females
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328	Adult	A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.	Adults
D001557	Benzenesulfonates	Organic salts and esters of benzenesulfonic acid.