Durable biochemical response following adrenal metastasectomy for oligometastatic castrate-resistant prostate cancer. 2020

Akbar N Ashrafi, and Carlos Fay, and Wesley Yip, and Daniel M de Freitas, and Jamal Nabhani, and Monish Aron
USC Institute of Urology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.

A 77 year-old man was referred to Urology with an enlarging left adrenal mass after treatment with androgen deprivation therapy for metastatic castrate-resistant prostate cancer. He underwent a robotic-assisted left radical adrenalectomy, with pathology revealing metastatic adenocarcinoma consistent with a primary prostate adenocarcinoma. The patient had a durable oncological response to metastasectomy with no evidence of biochemical or radiological recurrence after 5 years of follow-up. Adrenal metastases from prostate cancer are extremely rare, representing only 1% of metastatic cases. Surgical resection of oligometastatic prostate cancer recurrences may be considered in select patients and may improve progression-free survival.

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