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Complete biochemical response following metastasis-directed radiotherapy for oligometastatic prostate cancer: A case report. 2020
Satoshi Okuda, and
Ken-Ichi Tabata, and
Soichiro Shimura, and
Takahiro Harano, and
Izuru Shiba, and
Masatsugu Iwamura
Department of Urology, Kitasato University School of Medicine, Kanagawa, Japan.
Localized treatment has recently become an option for treating oligometastatic prostate cancer. Metastasis-directed therapy (MDT) is a new approach for localized treatment, and many clinical trials are ongoing. In the present case, biochemical recurrence occurred 8 months after a radical prostatectomy for localized prostate cancer, and oligometastases were diagnosed via whole-body magnetic resonance imaging. Metastasis-directed radiotherapy (MDRT) was performed on all oligometastatic sites. After MDRT without androgen deprivation therapy, the prostate-specific antigen (PSA) decreased to an undetectable level and did not increase for 24 months.
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