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Guidance on allergenicity assessment of genetically modified plants. 2017
, and
Hanspeter Naegeli, and
Andrew Nicholas Birch, and
Josep Casacuberta, and
Adinda De Schrijver, and
Mikolaj Antoni Gralak, and
Philippe Guerche, and
Huw Jones, and
Barbara Manachini, and
Antoine Messéan, and
Elsa Ebbesen Nielsen, and
Fabien Nogué, and
Christophe Robaglia, and
Nils Rostoks, and
Jeremy Sweet, and
Christoph Tebbe, and
Francesco Visioli, and
Jean-Michel Wal, and
Philippe Eigenmann, and
Michelle Epstein, and
Karin Hoffmann-Sommergruber, and
Frits Koning, and
Martinus Lovik, and
Clare Mills, and
Francisco Javier Moreno, and
Henk van Loveren, and
Regina Selb, and
Antonio Fernandez Dumont
This document provides supplementary guidance on specific topics for the allergenicity risk assessment of genetically modified plants. In particular, it supplements general recommendations outlined in previous EFSA GMO Panel guidelines and Implementing Regulation (EU) No 503/2013. The topics addressed are non-IgE-mediated adverse immune reactions to foods, in vitro protein digestibility tests and endogenous allergenicity. New scientific and regulatory developments regarding these three topics are described in this document. Considerations on the practical implementation of those developments in the risk assessment of genetically modified plants are discussed and recommended, where appropriate.
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