[On the enteral absorption of valproic acid (author's transl)]. 1977

W Oelkers, and G Stoffels, and H Schäfer, and H Reith

The absorption of valproic acid (dipropylacetic acid, DPA)--administered by capsules (free valproic acid) and dragees (valproate sodium)--has been studied. Regarding their bioavailability, both forms of administration examined are equivalent, which means that they are representing therapeutical alternatives.

UI MeSH Term Description Entries
D008297 Male Males
D002214 Capsules Hard or soft soluble containers used for the oral administration of medicine. Capsule,Microcapsule,Microcapsules
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D001682 Biological Availability The extent to which the active ingredient of a drug dosage form becomes available at the site of drug action or in a biological medium believed to reflect accessibility to a site of action. Availability Equivalency,Bioavailability,Physiologic Availability,Availability, Biologic,Availability, Biological,Availability, Physiologic,Biologic Availability,Availabilities, Biologic,Availabilities, Biological,Availabilities, Physiologic,Availability Equivalencies,Bioavailabilities,Biologic Availabilities,Biological Availabilities,Equivalencies, Availability,Equivalency, Availability,Physiologic Availabilities
D013607 Tablets Solid dosage forms, of varying weight, size, and shape, which may be molded or compressed, and which contain a medicinal substance in pure or diluted form. (Dorland, 28th ed) Tablet
D014631 Valerates Derivatives of valeric acid, including its salts and esters. Pentanoate,Pentanoates,Valerate
D014635 Valproic Acid A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS. Dipropyl Acetate,Divalproex,Sodium Valproate,2-Propylpentanoic Acid,Calcium Valproate,Convulsofin,Depakene,Depakine,Depakote,Divalproex Sodium,Ergenyl,Magnesium Valproate,Propylisopropylacetic Acid,Semisodium Valproate,Valproate,Valproate Calcium,Valproate Sodium,Valproic Acid, Sodium Salt (2:1),Vupral,2 Propylpentanoic Acid

Related Publications

W Oelkers, and G Stoffels, and H Schäfer, and H Reith
January 1978, Arzneimittel-Forschung,
W Oelkers, and G Stoffels, and H Schäfer, and H Reith
January 1981, Shika gakuho. Dental science reports,
W Oelkers, and G Stoffels, and H Schäfer, and H Reith
January 1978, Arzneimittel-Forschung,
W Oelkers, and G Stoffels, and H Schäfer, and H Reith
January 1980, Die Pharmazie,
W Oelkers, and G Stoffels, and H Schäfer, and H Reith
June 1975, Nihon Hifuka Gakkai zasshi. The Japanese journal of dermatology,
W Oelkers, and G Stoffels, and H Schäfer, and H Reith
October 1981, Der Nervenarzt,
W Oelkers, and G Stoffels, and H Schäfer, and H Reith
January 1981, Acta neurologica Belgica,
W Oelkers, and G Stoffels, and H Schäfer, and H Reith
October 1981, American journal of hospital pharmacy,
W Oelkers, and G Stoffels, and H Schäfer, and H Reith
January 1977, Arzneimittel-Forschung,
W Oelkers, and G Stoffels, and H Schäfer, and H Reith
July 1976, Medizinische Klinik,
Copied contents to your clipboard!