Biomaterial Database

Kikuchi-Fujimoto Disease Heralding Systemic Lupus Erythematosus. 2020

Jonathan A Aun, and Matthew J Hubbard

In this case report, the authors discuss a patient with a rare entity, Kikuchi Fujimoto Disease, which exhibited unique osteopathic structural examination findings, including enlarged cervical lymph nodes in conjunction with a Chapman reflex (CR). This report highlights the critical importance of histological examination of the lymph nodes. Additionally, it reminds physicians to consider the ways in which CR can potentially contribute to the diagnostic process.

UI	MeSH Term	Description	Entries
D008180	Lupus Erythematosus, Systemic	A chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys, and serosal membranes. It is of unknown etiology, but is thought to represent a failure of the regulatory mechanisms of the autoimmune system. The disease is marked by a wide range of system dysfunctions, an elevated erythrocyte sedimentation rate, and the formation of LE cells in the blood or bone marrow.	Libman-Sacks Disease,Lupus Erythematosus Disseminatus,Systemic Lupus Erythematosus,Disease, Libman-Sacks,Libman Sacks Disease
D008198	Lymph Nodes	They are oval or bean shaped bodies (1 - 30 mm in diameter) located along the lymphatic system.	Lymph Node,Node, Lymph,Nodes, Lymph
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D020042	Histiocytic Necrotizing Lymphadenitis	Development of lesions in the lymph node characterized by infiltration of the cortex or paracortex by large collections of proliferating histiocytes and complete or, more often, incomplete necrosis of lymphoid tissue.	Kikuchi Disease,Lymphadenitis, Histiocytic Necrotizing,Histiocytic Necrotising Lymphadenitis,Kikuchi Necrotizing Lymphadenitis,Kikuchi's Disease,Kikuchi-Fujimoto Disease,Kikuchi-Fujimoto's Disease,Nosocomial Kikuchi's Disease,Disease, Kikuchi,Disease, Kikuchi's,Disease, Kikuchi-Fujimoto,Disease, Kikuchi-Fujimoto's,Histiocytic Necrotising Lymphadenitides,Kikuchi Fujimoto Disease,Kikuchi Fujimoto's Disease,Kikuchi's Disease, Nosocomial,Kikuchi-Fujimotos Disease,Kikuchis Disease,Lymphadenitides, Histiocytic Necrotising,Lymphadenitis, Histiocytic Necrotising,Lymphadenitis, Kikuchi Necrotizing,Necrotising Lymphadenitides, Histiocytic,Necrotising Lymphadenitis, Histiocytic,Necrotizing Lymphadenitis, Histiocytic,Necrotizing Lymphadenitis, Kikuchi,Nosocomial Kikuchi Disease,Nosocomial Kikuchis Disease