Biomaterial Database

The role of the plasma membrane and intracellular organelles in synaptosomal calcium regulation. 1987

D G Nicholls, and T S Sihra, and J Sanchez-Prieto

Department of Biochemistry, University of Dundee, Scotland.

UI	MeSH Term	Description	Entries
D008928	Mitochondria	Semiautonomous, self-reproducing organelles that occur in the cytoplasm of all cells of most, but not all, eukaryotes. Each mitochondrion is surrounded by a double limiting membrane. The inner membrane is highly invaginated, and its projections are called cristae. Mitochondria are the sites of the reactions of oxidative phosphorylation, which result in the formation of ATP. They contain distinctive RIBOSOMES, transfer RNAs (RNA, TRANSFER); AMINO ACYL T RNA SYNTHETASES; and elongation and termination factors. Mitochondria depend upon genes within the nucleus of the cells in which they reside for many essential messenger RNAs (RNA, MESSENGER). Mitochondria are believed to have arisen from aerobic bacteria that established a symbiotic relationship with primitive protoeukaryotes. (King & Stansfield, A Dictionary of Genetics, 4th ed)	Mitochondrial Contraction,Mitochondrion,Contraction, Mitochondrial,Contractions, Mitochondrial,Mitochondrial Contractions
D002118	Calcium	A basic element found in nearly all tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.	Coagulation Factor IV,Factor IV,Blood Coagulation Factor IV,Calcium-40,Calcium 40,Factor IV, Coagulation
D002462	Cell Membrane	The lipid- and protein-containing, selectively permeable membrane that surrounds the cytoplasm in prokaryotic and eukaryotic cells.	Plasma Membrane,Cytoplasmic Membrane,Cell Membranes,Cytoplasmic Membranes,Membrane, Cell,Membrane, Cytoplasmic,Membrane, Plasma,Membranes, Cell,Membranes, Cytoplasmic,Membranes, Plasma,Plasma Membranes
D003600	Cytosol	Intracellular fluid from the cytoplasm after removal of ORGANELLES and other insoluble cytoplasmic components.	Cytosols
D005089	Exocytosis	Cellular release of material within membrane-limited vesicles by fusion of the vesicles with the CELL MEMBRANE.
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D013574	Synaptosomes	Pinched-off nerve endings and their contents of vesicles and cytoplasm together with the attached subsynaptic area of the membrane of the post-synaptic cell. They are largely artificial structures produced by fractionation after selective centrifugation of nervous tissue homogenates.	Synaptosome
D015388	Organelles	Specific particles of membrane-bound organized living substances present in eukaryotic cells, such as the MITOCHONDRIA; the GOLGI APPARATUS; ENDOPLASMIC RETICULUM; LYSOSOMES; PLASTIDS; and VACUOLES.	Organelle

Related Publications

D G Nicholls, and T S Sihra, and J Sanchez-Prieto

Intracellular calcium regulation, with special attention to the role of the plasma membrane calcium pump.

January 1988, Journal of cardiovascular pharmacology,

D G Nicholls, and T S Sihra, and J Sanchez-Prieto

Hormonal stimulation of Mg2+ uptake in hepatocytes. Regulation by plasma membrane and intracellular organelles.

July 1993, The Journal of biological chemistry,

D G Nicholls, and T S Sihra, and J Sanchez-Prieto

Calcium efflux and cycling across the synaptosomal plasma membrane.

February 1985, The Biochemical journal,

D G Nicholls, and T S Sihra, and J Sanchez-Prieto

Plasma membrane mechanisms for intracellular calcium regulation in squid axons.

January 1987, Acta physiologica et pharmacologica latinoamericana : organo de la Asociacion Latinoamericana de Ciencias Fisiologicas y de la Asociacion Latinoamericana de Farmacologia,

D G Nicholls, and T S Sihra, and J Sanchez-Prieto

Regulation of Cell Calcium and Role of Plasma Membrane Calcium ATPases.

January 2017, International review of cell and molecular biology,

D G Nicholls, and T S Sihra, and J Sanchez-Prieto

Transmembrane regulation of intracellular calcium by a plasma membrane sodium/calcium exchanger in mouse ova.

May 1999, Biology of reproduction,

D G Nicholls, and T S Sihra, and J Sanchez-Prieto

[Participation of calmodulin in the regulation of plasma membrane electric potential by intracellular calcium].

September 1983, Biokhimiia (Moscow, Russia),

D G Nicholls, and T S Sihra, and J Sanchez-Prieto

ER calcium and the functions of intracellular organelles.

February 2001, Seminars in cell & developmental biology,