Biomaterial Database

Danazol in the treatment of ureteral endometriosis. 1988

J M Jepsen, and K B Hansen

University Department of Obstetrics and Gynaecology, Kommunehospital, Aarhus, Denmark.

We report 2 cases of ureteral endometriosis in which initial hormonal management, including danazol, failed to reverse or to stop the progressing ureteral stenosis. After reviewing the various methods of treatment presented in the literature we conclude that solid documentation of the effect of danazol against ureteral endometriosis is lacking. To preserve kidney function we recommend resection of the affected portion of the ureter.

UI	MeSH Term	Description	Entries
D011245	Pregnadienes	Pregnane derivatives containing two double bonds anywhere within the ring structures.
D003613	Danazol	A synthetic steroid with antigonadotropic and anti-estrogenic activities that acts as an anterior pituitary suppressant by inhibiting the pituitary output of gonadotropins. It possesses some androgenic properties. Danazol has been used in the treatment of endometriosis and some benign breast disorders.	Azol,Cyclomen,Danatrol,Danazant,Danazol-Ratiopharm,Danocrine,Danol,Danoval,Ladogal,Norciden,Panacrine,Danazol Ratiopharm
D004715	Endometriosis	A condition in which functional endometrial tissue is present outside the UTERUS. It is often confined to the PELVIS involving the OVARY, the ligaments, cul-de-sac, and the uterovesical peritoneum.	Endometrioma,Endometriomas,Endometrioses
D005260	Female		Females
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328	Adult	A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.	Adults
D014516	Ureteral Neoplasms	Cancer or tumors of the URETER which may cause obstruction leading to hydroureter, HYDRONEPHROSIS, and PYELONEPHRITIS. HEMATURIA is a common symptom.	Cancer of Ureter,Ureteral Cancer,Cancer of the Ureter,Neoplasms of Ureter,Neoplasms, Ureteral,Ureter Cancer,Ureter Neoplasms,Ureter, Cancer Of,Cancer, Ureteral,Cancers, Ureteral,Neoplasm, Ureteral,Ureter Cancers,Ureter Neoplasm,Ureteral Cancers,Ureteral Neoplasm
D014517	Ureteral Obstruction	Blockage in any part of the URETER causing obstruction of urine flow from the kidney to the URINARY BLADDER. The obstruction may be congenital, acquired, unilateral, bilateral, complete, partial, acute, or chronic. Depending on the degree and duration of the obstruction, clinical features vary greatly such as HYDRONEPHROSIS and obstructive nephropathy.	Obstruction, Ureteral,Obstructions, Ureteral,Ureteral Obstructions