Biomaterial Database

The use of danazol for ureteral obstruction caused by endometriosis. 1981

B Gardner, and R H Whitaker

We report 2 successfully treated cases of unilateral obstruction owing to endometriosis. Treatment consisted of danazol alone in 1 case and surgical freeing of the obstructed ureter in the other. Danazol alone can reverse completely ureteral obstruction caused by endometriosis but if secondary fibrosis has occurred surgical treatment may be necessary. This is the first case reported of complete resolution of unilateral ureteral obstruction owing to endometriosis using danazol therapy alone.

UI	MeSH Term	Description	Entries
D011245	Pregnadienes	Pregnane derivatives containing two double bonds anywhere within the ring structures.
D003613	Danazol	A synthetic steroid with antigonadotropic and anti-estrogenic activities that acts as an anterior pituitary suppressant by inhibiting the pituitary output of gonadotropins. It possesses some androgenic properties. Danazol has been used in the treatment of endometriosis and some benign breast disorders.	Azol,Cyclomen,Danatrol,Danazant,Danazol-Ratiopharm,Danocrine,Danol,Danoval,Ladogal,Norciden,Panacrine,Danazol Ratiopharm
D004715	Endometriosis	A condition in which functional endometrial tissue is present outside the UTERUS. It is often confined to the PELVIS involving the OVARY, the ligaments, cul-de-sac, and the uterovesical peritoneum.	Endometrioma,Endometriomas,Endometrioses
D005260	Female		Females
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328	Adult	A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.	Adults
D014516	Ureteral Neoplasms	Cancer or tumors of the URETER which may cause obstruction leading to hydroureter, HYDRONEPHROSIS, and PYELONEPHRITIS. HEMATURIA is a common symptom.	Cancer of Ureter,Ureteral Cancer,Cancer of the Ureter,Neoplasms of Ureter,Neoplasms, Ureteral,Ureter Cancer,Ureter Neoplasms,Ureter, Cancer Of,Cancer, Ureteral,Cancers, Ureteral,Neoplasm, Ureteral,Ureter Cancers,Ureter Neoplasm,Ureteral Cancers,Ureteral Neoplasm
D014517	Ureteral Obstruction	Blockage in any part of the URETER causing obstruction of urine flow from the kidney to the URINARY BLADDER. The obstruction may be congenital, acquired, unilateral, bilateral, complete, partial, acute, or chronic. Depending on the degree and duration of the obstruction, clinical features vary greatly such as HYDRONEPHROSIS and obstructive nephropathy.	Obstruction, Ureteral,Obstructions, Ureteral,Ureteral Obstructions