Autonomous Distance Learning in Chemistry and Beyond! Using specific examples, some of which originate from online teaching in school during the COVID-19 lockdown in spring 2020, it is demonstrated how autonomous learning in chemistry can be supported, also in the long-term. Examples include the use of electronic media, experiments carried out at home, and discussion of current topics in the media that relate to chemistry to show how learning can be encouraged and the student motivation maintained. The aim is to encourage, on the one hand, self-guided learning to fulfill given study goals and on the other, autonomous learning out of curiosity and, later in life, to have the toolset to meet professional challenges.