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To assess the effect of anxiety on response to the Dexamethasone Suppression Test (DST), cortisol concentrations were determined in patients who had various diagnoses, with anxiety as a secondary characteristic. Saliva was collected before and after venepuncture at 4:05 PM following completion of the Leeds Questionnaire at 3:00 PM. Matrix effects, which caused an initial artefactual decrease in cortisol levels in some saliva samples in patients with high anxiety, could be eliminated by repeated freezing/thawing. There was no significant difference between salivary cortisol concentrations before and after venepuncture, indicating that variability in response to the DST is not a correlate of anxiety and stressful venepuncture. There was no association between anxiety scores and plasma or salivary cortisol values: thus, anxiety is unlikely to be a major contributory cause of nonsuppression of hypercortisolemia in the DST.
B Harris, and
N Cook, and
N Warner, and
G F Read, and
R F Walker, and
R Thomas, and
D Riad-Fahmy
November 1984,
Psychiatry research,
B Harris, and
N Cook, and
N Warner, and
G F Read, and
R F Walker, and
R Thomas, and
D Riad-Fahmy
February 1988,
Biological psychiatry,
B Harris, and
N Cook, and
N Warner, and
G F Read, and
R F Walker, and
R Thomas, and
D Riad-Fahmy
August 1984,
Biological psychiatry,
B Harris, and
N Cook, and
N Warner, and
G F Read, and
R F Walker, and
R Thomas, and
D Riad-Fahmy
September 1986,
The British journal of psychiatry : the journal of mental science,
B Harris, and
N Cook, and
N Warner, and
G F Read, and
R F Walker, and
R Thomas, and
D Riad-Fahmy
June 1987,
Yakubutsu, seishin, kodo = Japanese journal of psychopharmacology,
B Harris, and
N Cook, and
N Warner, and
G F Read, and
R F Walker, and
R Thomas, and
D Riad-Fahmy
January 2001,
Physiology & behavior,
B Harris, and
N Cook, and
N Warner, and
G F Read, and
R F Walker, and
R Thomas, and
D Riad-Fahmy
January 1987,
The Hillside journal of clinical psychiatry,
B Harris, and
N Cook, and
N Warner, and
G F Read, and
R F Walker, and
R Thomas, and
D Riad-Fahmy
September 1983,
Journal of the American Academy of Child Psychiatry,
B Harris, and
N Cook, and
N Warner, and
G F Read, and
R F Walker, and
R Thomas, and
D Riad-Fahmy
January 1988,
Psychiatrie, Neurologie und medizinische Psychologie. Beihefte,
B Harris, and
N Cook, and
N Warner, and
G F Read, and
R F Walker, and
R Thomas, and
D Riad-Fahmy
December 1983,
Canadian journal of psychiatry. Revue canadienne de psychiatrie,
