Biomaterial Database

Comparison of summating potential in Menière's disease between trans- and extratympanic electrocochleography. 1987

N Mori, and H Asai, and M Sakagami, and T Matsunaga

Department of Otolaryngology, Osaka University Medical School, Japan.

The summating potential (SP) recorded concurrently with transtympanic (TT) and extratympanic (ET) electrocochleography in Menière ears was compared with respect to polarity and amplitude. There was a difference in SP polarity and amplitude between the two methods. The incidence of the increase in the ratio of -SP amplitude to the amplitude of the auditory nerve action potential (AP) (-SP/AP ratio) at 80 dB nHL as a response to a click was higher with the ET than with the TT method. Most of the ears exhibiting an increased +SP/AP ratio with the TT method showed an increased -SP/AP ratio with the ET method. The incidence of increased SP/AP ratios including -SP/AP and +SP/AP ratios was similar with both methods. A +SP was recorded in 14 of 25 ears upon stimulation with an 8-kHz tone burst with the TT method, whereas no +SP was recorded in 25 ears with the ET method. Tone bursts of 1 and 2 kHz produced a -SP and similar waveforms with both methods. Comparison of -SP amplitude recorded with both methods revealed that the ratio of -SP amplitude with both methods is different across the stimulus frequencies. The present study suggests that the -SP elicited by tone bursts of mid to low frequencies is more stable in the diagnosis of Menière's disease than -SP elicited by a click because of the lesser influence of the electrode location and that the increase in the +SP recorded with the TT method may be of clinical significance in the diagnosis of Menière's disease.

UI	MeSH Term	Description	Entries
D008575	Meniere Disease	A disease of the inner ear (LABYRINTH) that is characterized by fluctuating SENSORINEURAL HEARING LOSS; TINNITUS; episodic VERTIGO; and aural fullness. It is the most common form of endolymphatic hydrops.	Meniere's Disease,Meniere's Syndrome,Vertigo, Aural,Auditory Vertigo,Aural Vertigo,Ménière Disease,Ménière's Disease,Ménière's Vertigo,Otogenic Vertigo,Auditory Vertigos,Disease, Meniere,Disease, Meniere's,Disease, Ménière,Disease, Ménière's,Diseases, Ménière,Diseases, Ménière's,Meniere Syndrome,Menieres Disease,Menieres Syndrome,Ménière Diseases,Ménière Vertigo,Ménière's Diseases,Ménière's Vertigos,Ménières Disease,Ménières Vertigo,Otogenic Vertigos,Syndrome, Meniere's,Vertigo, Auditory,Vertigo, Ménière's,Vertigo, Otogenic,Vertigos, Auditory,Vertigos, Ménière's,Vertigos, Otogenic
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D004566	Electrodes	Electric conductors through which electric currents enter or leave a medium, whether it be an electrolytic solution, solid, molten mass, gas, or vacuum.	Anode,Anode Materials,Cathode,Cathode Materials,Anode Material,Anodes,Cathode Material,Cathodes,Electrode,Material, Anode,Material, Cathode
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000200	Action Potentials	Abrupt changes in the membrane potential that sweep along the CELL MEMBRANE of excitable cells in response to excitation stimuli.	Spike Potentials,Nerve Impulses,Action Potential,Impulse, Nerve,Impulses, Nerve,Nerve Impulse,Potential, Action,Potential, Spike,Potentials, Action,Potentials, Spike,Spike Potential
D000328	Adult	A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.	Adults
D000368	Aged	A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available.	Elderly
D001300	Audiometry, Evoked Response	A form of electrophysiologic audiometry in which an analog computer is included in the circuit to average out ongoing or spontaneous brain wave activity. A characteristic pattern of response to a sound stimulus may then become evident. Evoked response audiometry is known also as electric response audiometry.	Audiometry, Electroencephalic Response,Electrocochleography,Evoked Response Audiometry,Audiometries, Electroencephalic Response,Audiometries, Evoked Response,Electrocochleographies,Electroencephalic Response Audiometries,Electroencephalic Response Audiometry,Evoked Response Audiometries,Response Audiometries, Electroencephalic,Response Audiometries, Evoked,Response Audiometry, Electroencephalic,Response Audiometry, Evoked