Lymphangiography and abdominal computerized tomography in persistent generalized lymphadenopathy. 1986

U Tirelli, and E Vaccher, and A Carbone, and P De Paoli, and S Morassut

Lymphangiography (LAG) and abdominal computed tomography (CT) were performed on 13 intravenous drug (heroin) abusers with persistent generalized lymphadenopathy (PGL). All 12 LAG performed were abnormal with a repetitive pattern of diffuse abnormalities of internal structures with small filling defects of both pelvic and abdominal lymph nodes. In 12/13 (92%) of the patients, lymphadenopathy was evidenced by CT scan as well. Retroperitoneal lymph nodes were always abnormal, mesenteric and pelvic nodes in 7 patients each. In 9/13 (69%) of the patients, the spleen was found to be moderately enlarged. The LAG films of our first 2 patients referred to us with an erroneous histologic diagnosis of malignant lymphoma were read to be consistent with involvement by lymphoma. Considering that patients with PGL are at risk for transformation to malignant lymphoma, the LAG and CT findings of PGL should be kept in mind when transformation to malignant lymphoma occurs and staging is performed.

UI MeSH Term Description Entries
D008198 Lymph Nodes They are oval or bean shaped bodies (1 - 30 mm in diameter) located along the lymphatic system. Lymph Node,Node, Lymph,Nodes, Lymph
D008206 Lymphatic Diseases Diseases of LYMPH; LYMPH NODES; or LYMPHATIC VESSELS. Lymphatism,Status Lymphaticus,Disease, Lymphatic,Diseases, Lymphatic,Lymphatic Disease
D008220 Lymphography Radiographic study of the lymphatic system following injection of dye or contrast medium. Lymphangiography,Lymphangiographies,Lymphographies
D008297 Male Males
D011860 Radiography, Abdominal Radiographic visualization of the body between the thorax and the pelvis, i.e., within the peritoneal cavity. Abdominal Radiography,Abdominal Radiographies,Radiographies, Abdominal
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000163 Acquired Immunodeficiency Syndrome An acquired defect of cellular immunity associated with infection by the human immunodeficiency virus (HIV), a CD4-positive T-lymphocyte count under 200 cells/microliter or less than 14% of total lymphocytes, and increased susceptibility to opportunistic infections and malignant neoplasms. Clinical manifestations also include emaciation (wasting) and dementia. These elements reflect criteria for AIDS as defined by the CDC in 1993. AIDS,Immunodeficiency Syndrome, Acquired,Immunologic Deficiency Syndrome, Acquired,Acquired Immune Deficiency Syndrome,Acquired Immuno-Deficiency Syndrome,Acquired Immuno Deficiency Syndrome,Acquired Immuno-Deficiency Syndromes,Acquired Immunodeficiency Syndromes,Immuno-Deficiency Syndrome, Acquired,Immuno-Deficiency Syndromes, Acquired,Immunodeficiency Syndromes, Acquired,Syndrome, Acquired Immuno-Deficiency,Syndrome, Acquired Immunodeficiency,Syndromes, Acquired Immuno-Deficiency,Syndromes, Acquired Immunodeficiency
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D013601 T-Lymphocytes Lymphocytes responsible for cell-mediated immunity. Two types have been identified - cytotoxic (T-LYMPHOCYTES, CYTOTOXIC) and helper T-lymphocytes (T-LYMPHOCYTES, HELPER-INDUCER). They are formed when lymphocytes circulate through the THYMUS GLAND and differentiate to thymocytes. When exposed to an antigen, they divide rapidly and produce large numbers of new T cells sensitized to that antigen. T Cell,T Lymphocyte,T-Cells,Thymus-Dependent Lymphocytes,Cell, T,Cells, T,Lymphocyte, T,Lymphocyte, Thymus-Dependent,Lymphocytes, T,Lymphocytes, Thymus-Dependent,T Cells,T Lymphocytes,T-Cell,T-Lymphocyte,Thymus Dependent Lymphocytes,Thymus-Dependent Lymphocyte

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