-transparent.png){kind=logo}
A 9-year-old boy suffering from T-cell acute lymphoblastic leukemia (T-ALL) with a mediastinal mass had a complete remission as a result of treatment. Ten months later, he developed a typical acute myelomonocytic leukemia (AMMoL) pattern. Two months after a second relapse, he showed a clinical picture that was indistinguishable from chronic myelocytic leukemia (CML). At autopsy, massive infiltration of CML-like cells was observed even in the thymus (190 g). These observations suggest that the leukemia in this child arose in a pluripotent stem cell capable of differentiation into both T-lymphocytic and myelomonocytic lineages.
Related Publications
J Shimizu, and
Y Hamashima, and
H Tsuda, and
Y Akiyama, and
H Mikawa, and
S Ikehara
March 2007,
Pediatric blood & cancer,
J Shimizu, and
Y Hamashima, and
H Tsuda, and
Y Akiyama, and
H Mikawa, and
S Ikehara
November 1978,
Pediatrics,
J Shimizu, and
Y Hamashima, and
H Tsuda, and
Y Akiyama, and
H Mikawa, and
S Ikehara
January 1987,
Hematologic pathology,
J Shimizu, and
Y Hamashima, and
H Tsuda, and
Y Akiyama, and
H Mikawa, and
S Ikehara
November 1978,
Blood,
J Shimizu, and
Y Hamashima, and
H Tsuda, and
Y Akiyama, and
H Mikawa, and
S Ikehara
May 1980,
American journal of clinical pathology,
J Shimizu, and
Y Hamashima, and
H Tsuda, and
Y Akiyama, and
H Mikawa, and
S Ikehara
June 2003,
International journal of hematology,
J Shimizu, and
Y Hamashima, and
H Tsuda, and
Y Akiyama, and
H Mikawa, and
S Ikehara
December 2020,
Clinical case reports,
J Shimizu, and
Y Hamashima, and
H Tsuda, and
Y Akiyama, and
H Mikawa, and
S Ikehara
September 2000,
[Rinsho ketsueki] The Japanese journal of clinical hematology,
J Shimizu, and
Y Hamashima, and
H Tsuda, and
Y Akiyama, and
H Mikawa, and
S Ikehara
December 2009,
La Revue du praticien,
J Shimizu, and
Y Hamashima, and
H Tsuda, and
Y Akiyama, and
H Mikawa, and
S Ikehara
February 1975,
JAMA,
