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Technetium-99m hexamethylpropyleneamineoxime ([99mTc]HM-PAO) brain single photon emission computed tomography (SPECT) was performed with a dual head rotating scintillation camera. Normal tracer distribution and side/side differences of counting rates were obtained in 11 healthy volunteers. Almost stable gray/white matter ratios were found (1.97-2.1) in one normal subject during 2 hr after tracer administration. Eighty-three investigated patients had the following diagnoses (in parentheses is percent of positive findings in each group): cerebral vascular disease 18 (94.4%), epilepsy 23 (82.6%), extrapyramidal disorders 8 (100%), dementia 12 (100%), headache 11 (63.6%), psychiatric disorders 11 (27.3%). In addition, SPECT was performed in 28 male volunteers during motor or visual imagery tasks and a significant increase (p = 0.035) of relative tracer deposition was observed in the left inferior occipital region during visual imagery when compared with motor imagery. The results indicate that [99mTc]HM-PAO SPECT is valuable for demonstrating pathologic and physiologic changes of the brain.
I Podreka, and
E Suess, and
G Goldenberg, and
M Steiner, and
T Brücke, and
C Müller, and
W Lang, and
R D Neirinckx, and
L Deecke
November 1989,
Journal of nuclear medicine : official publication, Society of Nuclear Medicine,
I Podreka, and
E Suess, and
G Goldenberg, and
M Steiner, and
T Brücke, and
C Müller, and
W Lang, and
R D Neirinckx, and
L Deecke
January 1985,
The Journal of nuclear medicine and allied sciences,
I Podreka, and
E Suess, and
G Goldenberg, and
M Steiner, and
T Brücke, and
C Müller, and
W Lang, and
R D Neirinckx, and
L Deecke
February 1988,
Clinical nuclear medicine,
I Podreka, and
E Suess, and
G Goldenberg, and
M Steiner, and
T Brücke, and
C Müller, and
W Lang, and
R D Neirinckx, and
L Deecke
January 1989,
Yonsei medical journal,
I Podreka, and
E Suess, and
G Goldenberg, and
M Steiner, and
T Brücke, and
C Müller, and
W Lang, and
R D Neirinckx, and
L Deecke
November 1989,
Journal of nuclear medicine : official publication, Society of Nuclear Medicine,
I Podreka, and
E Suess, and
G Goldenberg, and
M Steiner, and
T Brücke, and
C Müller, and
W Lang, and
R D Neirinckx, and
L Deecke
June 1990,
Journal of nuclear medicine : official publication, Society of Nuclear Medicine,
I Podreka, and
E Suess, and
G Goldenberg, and
M Steiner, and
T Brücke, and
C Müller, and
W Lang, and
R D Neirinckx, and
L Deecke
January 1988,
European journal of nuclear medicine,
I Podreka, and
E Suess, and
G Goldenberg, and
M Steiner, and
T Brücke, and
C Müller, and
W Lang, and
R D Neirinckx, and
L Deecke
May 1989,
Journal of nuclear medicine : official publication, Society of Nuclear Medicine,
I Podreka, and
E Suess, and
G Goldenberg, and
M Steiner, and
T Brücke, and
C Müller, and
W Lang, and
R D Neirinckx, and
L Deecke
June 1989,
Journal of nuclear medicine : official publication, Society of Nuclear Medicine,
I Podreka, and
E Suess, and
G Goldenberg, and
M Steiner, and
T Brücke, and
C Müller, and
W Lang, and
R D Neirinckx, and
L Deecke
November 1989,
Clinical nuclear medicine,
