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The radiolabeled monoclonal antibody 791T/36 raised against a human osteosarcoma was injected into 20 patients with known or suspected bone tumors. Gamma camera images were acquired at 48 or 72 hours after injection, and assessed for antibody localization. Positive images were obtained in all five osteosarcomas and four other primary malignant sarcomas. Two of the four other primary bone tumors gave positive images. Three patients with trauma had negative images as did one patient with Paget's disease. Two patients with suppurative disease gave positive images. The antibody localized in the majority of malignant sarcomas tested. In one tumor where tissue was available, a tumor:non-tumor ratio of 2.8:1 was measured. Repeat imaging was performed in five patients. Immunoscintigraphy using the monoclonal antibody 791T/36 has shown tumor localization in patients with bone and soft tissue sarcomas.
N C Armitage, and
A C Perkins, and
M V Pimm, and
M Wastie, and
J S Hopkins, and
F Dowling, and
R W Baldwin, and
J D Hardcastle
January 1986,
Hybridoma,
N C Armitage, and
A C Perkins, and
M V Pimm, and
M Wastie, and
J S Hopkins, and
F Dowling, and
R W Baldwin, and
J D Hardcastle
October 1998,
Hybridoma,
N C Armitage, and
A C Perkins, and
M V Pimm, and
M Wastie, and
J S Hopkins, and
F Dowling, and
R W Baldwin, and
J D Hardcastle
January 1987,
Placenta,
N C Armitage, and
A C Perkins, and
M V Pimm, and
M Wastie, and
J S Hopkins, and
F Dowling, and
R W Baldwin, and
J D Hardcastle
January 1991,
International orthopaedics,
N C Armitage, and
A C Perkins, and
M V Pimm, and
M Wastie, and
J S Hopkins, and
F Dowling, and
R W Baldwin, and
J D Hardcastle
April 1986,
Gan to kagaku ryoho. Cancer & chemotherapy,
N C Armitage, and
A C Perkins, and
M V Pimm, and
M Wastie, and
J S Hopkins, and
F Dowling, and
R W Baldwin, and
J D Hardcastle
February 2021,
Journal of immunological methods,
N C Armitage, and
A C Perkins, and
M V Pimm, and
M Wastie, and
J S Hopkins, and
F Dowling, and
R W Baldwin, and
J D Hardcastle
January 1989,
Toxicon : official journal of the International Society on Toxinology,
N C Armitage, and
A C Perkins, and
M V Pimm, and
M Wastie, and
J S Hopkins, and
F Dowling, and
R W Baldwin, and
J D Hardcastle
November 2022,
Journal of immunological methods,
N C Armitage, and
A C Perkins, and
M V Pimm, and
M Wastie, and
J S Hopkins, and
F Dowling, and
R W Baldwin, and
J D Hardcastle
April 2001,
Journal of virological methods,
N C Armitage, and
A C Perkins, and
M V Pimm, and
M Wastie, and
J S Hopkins, and
F Dowling, and
R W Baldwin, and
J D Hardcastle
January 1993,
Neoplasma,
