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34 patients with locally advanced or metastatic soft tissue sarcoma were treated with 4'-epi-adriamycin (4'-Epi-DX: 45 mg/m2 day 1 + 2) and cisplatinum (DDP: 90 mg/m2 day 2). If leukocyte- or plateletnadirs during the previous interval were above 2,000/mm3 or 70,000/mm3 the dose of 4'-Epi-DX was escalated for 5 mg/m2 per treatment day. One patient died tumor-related soon after the first treatment cycle. In 33 evaluable patients 4 (12%) complete remissions, 10 (30%) partial remissions and 15 (46%) no changes were observed. 4 patients (12%) had primary progressive disease under treatment. In 6 patients treatment was stopped because of side effects: 4 intractable nausea and vomiting, 1 ototoxicity, 1 supposed cardiomyopathy. Hematotoxicity was not a limiting factor in this treatment regimen.
H Sauer, and
W Mair, and
U Fink, and
H Rückle, and
I Mjaaland, and
W Wilmanns
July 1993,
Journal of clinical oncology : official journal of the American Society of Clinical Oncology,
H Sauer, and
W Mair, and
U Fink, and
H Rückle, and
I Mjaaland, and
W Wilmanns
November 1984,
Cancer treatment reports,
H Sauer, and
W Mair, and
U Fink, and
H Rückle, and
I Mjaaland, and
W Wilmanns
January 2000,
Journal of surgical oncology,
H Sauer, and
W Mair, and
U Fink, and
H Rückle, and
I Mjaaland, and
W Wilmanns
June 2020,
American journal of clinical oncology,
H Sauer, and
W Mair, and
U Fink, and
H Rückle, and
I Mjaaland, and
W Wilmanns
August 2000,
Investigational new drugs,
H Sauer, and
W Mair, and
U Fink, and
H Rückle, and
I Mjaaland, and
W Wilmanns
January 2010,
Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association,
H Sauer, and
W Mair, and
U Fink, and
H Rückle, and
I Mjaaland, and
W Wilmanns
April 1992,
Annals of oncology : official journal of the European Society for Medical Oncology,
H Sauer, and
W Mair, and
U Fink, and
H Rückle, and
I Mjaaland, and
W Wilmanns
January 1988,
Seminars in surgical oncology,
H Sauer, and
W Mair, and
U Fink, and
H Rückle, and
I Mjaaland, and
W Wilmanns
January 1985,
Voprosy onkologii,
H Sauer, and
W Mair, and
U Fink, and
H Rückle, and
I Mjaaland, and
W Wilmanns
January 1989,
Cancer treatment and research,
