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A nanodevice with lifetime-improved singlet oxygen for enhanced photodynamic therapy. 2022
A-Min Cao, and
Wen-Long Liu, and
Mei-Zhen Zou, and
Si-Yong Qin, and
Yin-Jia Cheng, and
Ai-Qing Zhang
Key Laboratory of Catalysis and Energy Materials Chemistry of Ministry of Education & Hubei Key Laboratory of Catalysis and Materials Science, School of Chemistry and Materials Science, South-Central Minzu University, Wuhan, 430074, P. R. China. wenlong@whu.edu.cn.
The short lifetime of singlet oxygen reduces its accumulation in the endoplasmic reticulum, which limits the output of photodynamic therapy. A nanodevice with functions of singlet oxygen production, storage and release can improve the lifetime of singlet oxygen for enhancing phototherapeutic efficacy.
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