-transparent.png){kind=logo}
A DNA fragment encoding the carboxy terminal 80% of the Plasmodium berghei circumsporozoite protein was selected from a genomic DNA expression library. Sequencing revealed that the P. berghei circumsporozoite protein was similar in overall structure to circumsporozoite proteins from other malaria species, although the central repeat region was unique in comprising two different blocks of tandem peptide repeats: 11 eight amino acid repeats with predominant sequence DPAPPNAN were followed by 16 two amino repeats, predominantly PQ. The P. berghei circumsporozoite protein exhibited limited, but about equal amino acid homology to circumsporozoite proteins from P. knowlesi, P. vivax, and P. falciparum, indicating that P. berghei is not closely related to any of these other malaria species. Cloning of the P. berghei circumsporozoite protein gene will allow direct testing of sporozoite vaccines in mice.
J L Weber, and
J E Egan, and
J A Lyon, and
R A Wirtz, and
Y Charoenvit, and
W L Maloy, and
W T Hockmeyer
November 1986,
Molecular and cellular biology,
J L Weber, and
J E Egan, and
J A Lyon, and
R A Wirtz, and
Y Charoenvit, and
W L Maloy, and
W T Hockmeyer
January 1990,
Nucleic acids research,
J L Weber, and
J E Egan, and
J A Lyon, and
R A Wirtz, and
Y Charoenvit, and
W L Maloy, and
W T Hockmeyer
November 1985,
Science (New York, N.Y.),
J L Weber, and
J E Egan, and
J A Lyon, and
R A Wirtz, and
Y Charoenvit, and
W L Maloy, and
W T Hockmeyer
May 2005,
Cellular microbiology,
J L Weber, and
J E Egan, and
J A Lyon, and
R A Wirtz, and
Y Charoenvit, and
W L Maloy, and
W T Hockmeyer
December 1988,
European journal of immunology,
J L Weber, and
J E Egan, and
J A Lyon, and
R A Wirtz, and
Y Charoenvit, and
W L Maloy, and
W T Hockmeyer
February 1990,
Molecular and biochemical parasitology,
J L Weber, and
J E Egan, and
J A Lyon, and
R A Wirtz, and
Y Charoenvit, and
W L Maloy, and
W T Hockmeyer
January 1997,
Molecular and biochemical parasitology,
J L Weber, and
J E Egan, and
J A Lyon, and
R A Wirtz, and
Y Charoenvit, and
W L Maloy, and
W T Hockmeyer
September 1991,
Molecular and biochemical parasitology,
J L Weber, and
J E Egan, and
J A Lyon, and
R A Wirtz, and
Y Charoenvit, and
W L Maloy, and
W T Hockmeyer
November 2020,
eLife,
J L Weber, and
J E Egan, and
J A Lyon, and
R A Wirtz, and
Y Charoenvit, and
W L Maloy, and
W T Hockmeyer
December 1984,
Proceedings of the National Academy of Sciences of the United States of America,
